Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 2895914..2896466 Replicon chromosome
Accession NZ_CP081257
Organism Phaeobacter inhibens strain M636

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag K4L01_RS13800 Protein ID WP_260099096.1
Coordinates 2896146..2896466 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag K4L01_RS13795 Protein ID WP_260099095.1
Coordinates 2895914..2896159 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K4L01_RS13785 (K4L01_13760) 2891529..2893232 + 1704 WP_260099093.1 hypothetical protein -
K4L01_RS13790 (K4L01_13765) 2893300..2895420 + 2121 WP_260099094.1 hypothetical protein -
K4L01_RS13795 (K4L01_13770) 2895914..2896159 + 246 WP_260099095.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
K4L01_RS13800 (K4L01_13775) 2896146..2896466 + 321 WP_260099096.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K4L01_RS13805 (K4L01_13780) 2896591..2898435 + 1845 WP_260099097.1 type IV secretory system conjugative DNA transfer family protein -
K4L01_RS13810 (K4L01_13785) 2898528..2898809 + 282 WP_260099098.1 hypothetical protein -
K4L01_RS13815 (K4L01_13790) 2898817..2899140 - 324 WP_260099099.1 H-NS histone family protein -
K4L01_RS13820 (K4L01_13795) 2899409..2901016 + 1608 WP_260099100.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2886844..2911395 24551


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(11-97)

Antitoxin

Antitoxin ParD

(1-80)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12155.84 Da        Isoelectric Point: 4.6104

>T212755 WP_260099096.1 NZ_CP081257:2896146-2896466 [Phaeobacter inhibens]
MRTSEPLELTLSLKAQSDLEEIWLYSAQVWGRDQADLYLNTLQSVFETLCDLPELAREYEELSPAVRMHQTGQHVVIYRV
QGSQLQIIRVLGARQNWRAVLAALDA

Download         Length: 321 bp

>T212755 NZ_CP107346:c78124-77708 [Klebsiella pneumoniae]
GTGAACAAGACCTATATGCTCGACACCTGTATCTGCTCGTTCATCATGCGCGAGCAGCCGGAAGCCGTCCTGAAGCGCCT
GGAGCAGGCGGTGCTGCGCGGCCAGCGCATCGTTGTCTCGGCCATCACTTATTCTGAAATGCGCTTCGGGGCCACCGGCC
CGAAGGCCTCCCCGCGCCACGTCGAGCTGGTCGACGCGTTCTGCGCCCGCCTCGATGCCATCCTGCCCTGGGATCGCGCT
GCGGTGGACGCCACCACGGAGATTAAGGTGGCGCTGCGAATGGCCGGGACGCCGATCGGCCCGAACGACACGGCCATTGC
CGGGCACGCCATCGCCGCCGGTGCCGTGCTGGTGACGAATAATACGCGGGAATTTGAGCGGGTACCGGGTCTTGTGCTGG
AAGACTGGGTAAGATAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9261.29 Da        Isoelectric Point: 4.4523

>AT212755 WP_260099095.1 NZ_CP081257:2895914-2896159 [Phaeobacter inhibens]
METIDIALPDPMKAWVETQTEEGRYSDTSDYVQHLIRRDQTRQQALNILQTAVTEGIESGLDGPFDMETFKARLHKTHAD
V

Download         Length: 246 bp

>AT212755 NZ_CP107346:c78351-78121 [Klebsiella pneumoniae]
ATGAGAACTGTATCCATTTTTAAAAACGGCAATAACCGCGCCATTCGTCTGCCCCGCGATCTGGATTTTGAGGGAGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATTATTTTGCGTCCCGTCCGGCCGACCTGGGGCTCGTTCGCGCAGTTCG
AGAAGGCAGACCCGGACTTTATGGCGGAGCGCGAGGACGTTGTCAGCGACGAAGGACGATTTAACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References