212740

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 5115536..5116052 Replicon chromosome
Accession NZ_CP081201
Organism Pseudomonas phytophila strain ICMP 23753

Toxin (Protein)


Gene name stbE Uniprot ID A0A2G0VJ60
Locus tag K3169_RS23170 Protein ID WP_027900068.1
Coordinates 5115771..5116052 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2G0VJ75
Locus tag K3169_RS23165 Protein ID WP_027900067.1
Coordinates 5115536..5115781 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K3169_RS23160 (K3169_23005) 5111450..5115361 - 3912 WP_263268199.1 ATP-dependent RNA helicase HrpA -
K3169_RS23165 (K3169_23010) 5115536..5115781 + 246 WP_027900067.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
K3169_RS23170 (K3169_23015) 5115771..5116052 + 282 WP_027900068.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K3169_RS23175 (K3169_23020) 5116279..5117970 - 1692 WP_122397383.1 long-chain-fatty-acid--CoA ligase FadD1 -
K3169_RS23180 (K3169_23025) 5118668..5120356 - 1689 WP_263268202.1 long-chain-fatty-acid--CoA ligase FadD2 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-81)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-69)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10688.46 Da        Isoelectric Point: 10.5054

>T212740 WP_027900068.1 NZ_CP081201:5115771-5116052 [Pseudomonas phytophila]
MTFKLEFLPSALKEWEKLGHTIRDQLKKKLQERLSLPRVPGDALHGMPDHYKIKLRSAGYRLVYRVEDDRVVVTVVAVGK
RERGDVYAAAGNR

Download         Length: 282 bp

>T212740 NZ_CP107343:c6346-6032 [Klebsiella pneumoniae]
ATGCCACAGGTAACGATTTCCGCGCTGGCACAGCGCGATTTACAACGCCTTCAGGACTTTCTCAAAACCAAAAATCGGCT
GGCAGCCAGAAAAGGAGGTGAGGTGATCGTCCGGGCTATCCAGCAACTGAAAACATTGCCAGACATTGGCCGCCCGGTGC
CGTTTCTGCCGCTGGAATATAAGGAACTGGTGATCGGGTTTGGCGACAGTGGCTATGTGATGCTCTACCGCCACGACCGG
GAAATGGACCAGATTGTGATCGTCACCGTCAGGCATCAGAAAGAATCCGGGTATCCGGGGGCAGACAGCCTCTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8837.26 Da        Isoelectric Point: 4.5200

>AT212740 WP_027900067.1 NZ_CP081201:5115536-5115781 [Pseudomonas phytophila]
MQSILADIAVSVSELKKNPSAVLSGAHGLPVAVLNHNKVMGYMVPAEVFEAMMERLDDLDLADLIKSRQHEKPVPVDIDD
L

Download         Length: 246 bp

>AT212740 NZ_CP107343:c6612-6334 [Klebsiella pneumoniae]
ATGTCATCAGCAACATCCATCAGGCTCGATGAAGAACTTAAGGACCGGCTGAAAACGCTGGCCGATGACCGGCACCGCTC
AGCGCACGCGCTAATGCTGGAGGCAATCACCGAATACATCGACCGGGAAGAGAAGCGCAGCCAGTACCTGCGGGACGGAC
AGGCCGCATGGCAGCACTATCAGGAAACGGGTCTGCACCTTACTGCGGAAGAAGCGGAAGCCTGGATAAGTACCTGGGGA
ACTGAGAACGAGCAGGATGCTCCGCCATGCCACAGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2G0VJ60

Antitoxin

Source ID Structure
AlphaFold DB A0A2G0VJ75

References