Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 5655851..5656376 Replicon chromosome
Accession NZ_CP081200
Organism Pseudomonas sp. 3-2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag K3819_RS25665 Protein ID WP_085612534.1
Coordinates 5656080..5656376 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K3819_RS25660 Protein ID WP_085608779.1
Coordinates 5655851..5656090 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K3819_RS25635 (K3819_25635) 5651681..5652142 + 462 WP_042610602.1 GNAT family N-acetyltransferase -
K3819_RS25640 (K3819_25640) 5652370..5653020 + 651 WP_011336118.1 DedA family protein -
K3819_RS25645 (K3819_25645) 5653025..5653837 + 813 WP_221398176.1 zinc-dependent peptidase -
K3819_RS25650 (K3819_25650) 5653952..5654479 + 528 WP_007933577.1 inorganic diphosphatase -
K3819_RS25655 (K3819_25655) 5654701..5655441 + 741 WP_221398177.1 helix-turn-helix transcriptional regulator -
K3819_RS25660 (K3819_25660) 5655851..5656090 + 240 WP_085608779.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
K3819_RS25665 (K3819_25665) 5656080..5656376 + 297 WP_085612534.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K3819_RS25670 (K3819_25670) 5656438..5657250 - 813 WP_221398178.1 DUF2135 domain-containing protein -
K3819_RS25675 (K3819_25675) 5657254..5658873 - 1620 WP_221398179.1 DUF2300 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-79)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11561.33 Da        Isoelectric Point: 9.3768

>T212735 WP_085612534.1 NZ_CP081200:5656080-5656376 [Pseudomonas sp. 3-2]
MTYNLEFDRRALKEWNKLGDTIREQFKKKLSEVLENPRIEANRLRELPDCYKVKLKSAGYRLIYQVIDLEIVVFVVAIGK
REREAAYDAAQDRLSSQP

Download         Length: 297 bp

>T212735 NZ_CP107341:3148779-3149126 [Klebsiella pneumoniae]
ATGTGGGATGTAGAAACGACGGATACGTTTGATGCCTGGTTCGAATTACAAAGTAGAGCTTTAAAAGAGGATATGTTGGC
CACGATGCTCATCCTGTCTGAGTTTGCTCCGCAGCTTGGGCGCCCGTATGTTGATACGGTGAAAGATTCAACGTTTCAGA
ATATGAAAGAACTGCGGGTTCAGCATCATGGGCTCCCCATCCGCGCCTGTTTTGCTTTTGATCCTCTGCGGAAAGCTATC
GTTTTATGTGTGGGCAATAAGGATGGCATGAATGAGAAACGTTTTTACAAAGAGATGATTACTCTGGCTGACAGAGAATT
CAGCCAACACCTGACTAAGGAGCGATAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8821.23 Da        Isoelectric Point: 4.8146

>AT212735 WP_085608779.1 NZ_CP081200:5655851-5656090 [Pseudomonas sp. 3-2]
MASINIRIDDELKKRAFAELEKLGLSPSELLRQTLQYVADRGKLPFKAALLSEEDEALIAVVTERLAAPQRVKVSLDDL

Download         Length: 240 bp

>AT212735 NZ_CP107341:3149126-3149425 [Klebsiella pneumoniae]
ATGGCCACGCTAAAAGAACTCATGGCGAAACAGAGTCCTGATAGCCAGCAGCGTATTGCAGCGAAAGCGGCAGAGATACG
CCAGTCTGTCGCTTTAAACTTGCTTCGAGAAGAGTTGCAAATGTCGCAAACAGAGATGGCTGCGGCTATGGGGGTAAAGC
AGCCAACGATCGCTAAAATGGAACAGGCTGATAACGACCCTCGGCTTTCGACCCTAAAACGCTACATTGCGGCATTGGGG
GGAGAACTCAGTATAAATGTCACATTGCCGACTGGAAAAAAAGTCTCGTTTAATTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References