Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 38491..39022 Replicon plasmid unnamed3
Accession NZ_CP081047
Organism Leisingera aquaemixtae strain M597

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag K3552_RS19255 Protein ID WP_260014085.1
Coordinates 38491..38793 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag K3552_RS19260 Protein ID WP_260014087.1
Coordinates 38786..39022 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K3552_RS19235 (K3552_19190) 34955..35638 + 684 WP_260014080.1 hypothetical protein -
K3552_RS19240 (K3552_19195) 35744..37018 + 1275 WP_260014081.1 Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB -
K3552_RS19245 (K3552_19200) 37086..37520 + 435 WP_260014082.1 GFA family protein -
K3552_RS19250 (K3552_19205) 37530..38441 - 912 WP_260014084.1 MurR/RpiR family transcriptional regulator -
K3552_RS19255 (K3552_19210) 38491..38793 - 303 WP_260014085.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K3552_RS19260 (K3552_19215) 38786..39022 - 237 WP_260014087.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
K3552_RS19265 (K3552_19220) 39167..43024 - 3858 WP_260014153.1 PEP/pyruvate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - clpV1 / hsiC1/vipB / hsiB1/vipA 1..108896 108896


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-93)

Antitoxin

Antitoxin ParD

(6-74)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11543.22 Da        Isoelectric Point: 6.8804

>T212629 WP_260014085.1 NZ_CP081047:c38793-38491 [Leisingera aquaemixtae]
MAEPRWRIRPAARADLAAIWRYGRDTWGAAQADAYTDSLFALFDLLADFPEMARERAEFTPPVRIHPSGAHLVLYRLEHG
RPEILRILHARQDLMAFLSE

Download         Length: 303 bp

>T212629 NZ_CP107303:c1851973-1851566 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCGTGC
GCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCCGAA
TGGGAAATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGGACA
GCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGGCGC
AGGAGTAA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8474.43 Da        Isoelectric Point: 4.6721

>AT212629 WP_260014087.1 NZ_CP081047:c39022-38786 [Leisingera aquaemixtae]
MATMNVSLPDQMKDWVEEQARTGTYANSSDYVRDLIRRDQARTAAIAELQSAIDAGLASGPAEPLSAESFKAAMRRNG

Download         Length: 237 bp

>AT212629 NZ_CP107303:c1852220-1851954 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References