21261

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 120752..122090 Replicon chromosome
Accession NC_007482
Organism Pseudoalteromonas haloplanktis TAC125

Toxin (Protein)


Gene name sanaT Uniprot ID A0A379I3A9
Locus tag PSHA_RS15360 Protein ID WP_041454885.1
Coordinates 121140..122090 (+) Length 317 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID A0A1R4KHH7
Locus tag PSHA_RS15355 Protein ID WP_011329741.1
Coordinates 120752..121150 (+) Length 133 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSHA_RS15340 116678..117769 - 1092 WP_011329738.1 DNA sulfur modification protein DndB -
PSHA_RS15345 117905..119032 + 1128 WP_011329739.1 cysteine desulfurase DndA -
PSHA_RS15350 119440..120444 - 1005 WP_011329740.1 NERD domain-containing protein -
PSHA_RS15355 120752..121150 + 399 WP_011329741.1 hypothetical protein Antitoxin
PSHA_RS15360 121140..122090 + 951 WP_041454885.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
PSHA_RS15365 122413..123363 - 951 WP_011329743.1 glutathione S-transferase family protein -
PSHA_RS15370 123441..123896 - 456 WP_011329744.1 DoxX family protein -
PSHA_RS15375 124040..124927 + 888 WP_011329745.1 LysR family transcriptional regulator -
PSHA_RS15380 125020..126747 - 1728 WP_011329746.1 potassium/proton antiporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(35-300)

Antitoxin

Protein of unknown function DUF6088

(16-70)


Sequences

Toxin        


Download         Length: 317 a.a.        Molecular weight: 36104.57 Da        Isoelectric Point: 6.6082

>T21261 WP_041454885.1 NC_007482:121140-122090 [Pseudoalteromonas translucida]
MLIDSDLFLDVADALGMGNPAIVEKDYYVVALLKLLSELSFDTHLLVFSGGTALTKSGIKTHRMSEDIDIKIIPTDVFAN
ISKTQKRKARKELHLQLLNAISLHNSFSVENRPTIYDEYRYQQIDIRYPQAHSKVPCLRPFIKLELIETLLYDQVVSRDI
CSLMNEVTQKPPEVALMGFSSIKSTQAEKLVSMLRRTASFARDNIRDDDPALIRHIYDTYYIQQAGLASASDVMSLVSKV
IAEDLTRYSNQHAEFMKSPIAELKFGLSLLQTNTLYEERFNQYVVPMVYGNNSLNWQQAFDVFKLYCNQVLNNIKL

Download         Length: 951 bp

>T21261 NC_007482:121140-122090 [Pseudoalteromonas translucida]
ATGCTAATTGATAGTGACCTGTTTTTAGATGTTGCCGATGCTCTTGGTATGGGTAACCCTGCTATTGTTGAAAAAGATTA
TTATGTTGTTGCATTACTAAAACTACTTTCTGAATTGTCTTTTGATACGCACTTATTGGTTTTTTCTGGTGGTACCGCAT
TAACAAAGTCGGGCATTAAAACTCATCGAATGTCTGAAGACATTGATATTAAAATCATACCTACAGATGTGTTTGCTAAT
ATTTCAAAAACACAAAAAAGAAAGGCTAGGAAAGAGTTACATCTTCAATTACTTAATGCCATTAGTCTGCACAACTCTTT
TTCGGTAGAAAACCGCCCTACTATTTATGATGAATATCGTTATCAACAAATTGATATACGTTATCCTCAAGCACATTCAA
AAGTTCCATGCCTAAGGCCGTTTATTAAGTTAGAGCTGATAGAGACCTTGCTTTATGATCAAGTAGTGAGTAGAGATATA
TGTTCTTTAATGAATGAGGTCACTCAAAAGCCTCCTGAAGTTGCGCTAATGGGGTTTTCGAGTATTAAGAGTACACAAGC
GGAAAAGCTAGTCTCTATGTTGAGGCGAACAGCAAGTTTTGCGCGCGATAATATAAGAGATGATGATCCTGCATTAATAC
GCCATATTTATGATACGTATTATATTCAACAAGCTGGGCTTGCGAGTGCTTCTGACGTAATGTCTTTGGTAAGTAAAGTT
ATTGCGGAAGACTTAACGCGTTACTCAAACCAACACGCTGAATTTATGAAAAGTCCGATTGCTGAACTGAAGTTTGGCTT
AAGCTTACTACAAACCAATACATTATATGAAGAACGCTTTAACCAATATGTAGTACCTATGGTTTATGGCAATAATAGCC
TTAATTGGCAGCAAGCATTTGATGTATTTAAGTTATATTGCAATCAAGTGTTAAATAACATAAAGCTTTAG

Antitoxin


Download         Length: 133 a.a.        Molecular weight: 14701.93 Da        Isoelectric Point: 10.5773

>AT21261 WP_011329741.1 NC_007482:120752-121150 [Pseudoalteromonas translucida]
MTIASKVTTRINRSKRYVFDRADFADIAGYDQVGRVLKKLVDNGHLLRIGYGLYTKARENRITGKLMPASPAGADGVILE
AIEKLGVDYKFDEFSQRSINGESLQIPASLKIITNNRFKRKIVVNNSAINAN

Download         Length: 399 bp

>AT21261 NC_007482:120752-121150 [Pseudoalteromonas translucida]
ATGACAATAGCAAGTAAAGTAACAACAAGAATAAACCGCTCAAAGCGTTATGTTTTTGATCGTGCTGATTTTGCAGATAT
TGCTGGTTACGACCAAGTTGGCCGGGTATTAAAAAAGCTGGTTGATAATGGTCATTTATTGCGTATTGGTTATGGGCTTT
ACACTAAAGCGAGAGAAAATCGCATTACGGGTAAGTTAATGCCGGCATCTCCTGCGGGAGCTGATGGTGTTATATTAGAA
GCGATTGAAAAGCTAGGTGTTGACTACAAATTTGATGAGTTTTCACAACGTAGTATCAATGGTGAAAGCTTGCAAATTCC
AGCGTCTCTGAAAATAATTACAAATAATCGCTTTAAACGCAAAATTGTCGTAAATAATAGTGCTATTAATGCTAATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A379I3A9

Antitoxin

Source ID Structure
AlphaFold DB A0A1R4KHH7

References