Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2977295..2977842 Replicon chromosome
Accession NZ_CP081016
Organism Pseudomonas sp. 2hn

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag K2O50_RS13400 Protein ID WP_050705773.1
Coordinates 2977295..2977570 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K2O50_RS13405 Protein ID WP_050705772.1
Coordinates 2977570..2977842 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K2O50_RS13370 (K2O50_13370) 2972592..2972828 + 237 WP_028688843.1 hypothetical protein -
K2O50_RS13375 (K2O50_13375) 2972905..2973213 + 309 WP_050705778.1 DUF3077 domain-containing protein -
K2O50_RS13380 (K2O50_13380) 2973408..2973971 + 564 WP_050705777.1 hypothetical protein -
K2O50_RS13385 (K2O50_13385) 2973996..2974379 + 384 WP_050705776.1 hypothetical protein -
K2O50_RS13390 (K2O50_13390) 2974520..2975257 - 738 WP_050705775.1 hypothetical protein -
K2O50_RS13395 (K2O50_13395) 2975538..2977145 + 1608 WP_050705774.1 methyl-accepting chemotaxis protein -
K2O50_RS13400 (K2O50_13400) 2977295..2977570 - 276 WP_050705773.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K2O50_RS13405 (K2O50_13405) 2977570..2977842 - 273 WP_050705772.1 ribbon-helix-helix domain-containing protein Antitoxin
K2O50_RS13410 (K2O50_13410) 2978054..2980291 - 2238 WP_050705771.1 TonB-dependent receptor -
K2O50_RS13415 (K2O50_13415) 2980529..2981491 - 963 WP_050705770.1 siderophore ABC transporter substrate-binding protein -
K2O50_RS13420 (K2O50_13420) 2981488..2982270 - 783 WP_050705769.1 ATP-binding cassette domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2962759..2977842 15083


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10660.28 Da        Isoelectric Point: 8.5491

>T212589 WP_050705773.1 NZ_CP081016:c2977570-2977295 [Pseudomonas sp. 2hn]
MDLKWTSKALSDIARLYEFLAAVNKPAAVRTVQQLTGAASMLLANPRIGERLEEFEPRDVRRIQIGHYEMRYEIADSTLF
LLRLWHTREDR

Download         Length: 276 bp

>T212589 NZ_CP107287:c30004-29756 [Escherichia coli]
ATGAGAAAAAATAAAGGCGATGTGACTTATTTTCTTGAAAAAGAAGGTGACAATTACAGGCTTACAAAAAGGATAAAAGC
CAGAACAAATGTTAAAATCGGGAACAAAACTACGAAAATTACATTGTATGATGCCGTACTGAATGAGAATGAATTACAAC
ATATTGATTTTACGTGTGCCGGATTAAGGGAAGACGATGAGACGCCAGTTAAAAATTTAATTAAGGAGTTTATGTTAAAT
GAAACCTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10153.55 Da        Isoelectric Point: 5.6994

>AT212589 WP_050705772.1 NZ_CP081016:c2977842-2977570 [Pseudomonas sp. 2hn]
MATTIKTRSVTAHVPVQLAEKVDLLAERLERSKNWIVKQALIAWIDQEEERSRLTREALADVDANRVIDHQAVQAWADSL
GTDTPLPVPR

Download         Length: 273 bp

>AT212589 NZ_CP107287:c29766-29539 [Escherichia coli]
ATGAAACCTGATAATACACCTGAAAATGTAAAAAAATTACGTTTAAAAGCAGGATTAACACAAAAGGAATGCAGTCATAT
TTATGGTGTTGGGCTAAGAACCTGGCAGAAAAAAGAGGAAGTTAATACTCAAAACAGTCAAAGTCTGTCACTGGTTGAGT
TTGAGTTTCTTTTGTTACTTGCAGGAGAACATCCTGAATACGTGCTCTGCAAAAGGGAGTCAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References