Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2219715..2219983 Replicon chromosome
Accession NZ_CP081010
Organism Escherichia coli strain 25POL

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2219843..2219945 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2219715..2219983 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K3072_RS10330 2216267..2216929 - 663 WP_000944256.1 exodeoxyribonuclease X -
K3072_RS10335 2216953..2217609 - 657 WP_000011644.1 carbon-nitrogen hydrolase family protein YobB -
K3072_RS10340 2217712..2217942 - 231 WP_000916763.1 DNA polymerase III subunit theta -
K3072_RS10345 2218081..2218455 + 375 WP_000168747.1 CopC domain-containing protein YobA -
K3072_RS10350 2218459..2219331 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
K3072_RS10355 2219344..2219685 + 342 WP_000984819.1 YebY family protein -
- 2219715..2219983 - 269 - - Antitoxin
- 2219843..2219945 + 103 - - Toxin
K3072_RS10360 2220080..2220736 + 657 WP_000812743.1 protein-serine/threonine phosphatase -
K3072_RS10365 2220737..2220928 - 192 WP_001317886.1 YebW family protein -
K3072_RS10370 2221033..2221269 - 237 WP_001295499.1 YebV family protein -
K3072_RS10375 2221387..2222826 - 1440 WP_001704100.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T212559 NZ_CP081010:2219843-2219945 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT212559 NZ_CP081010:c2219983-2219715 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References