Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) unclassified/Polyketide_cyc2(toxin)
Location 4383311..4383974 Replicon chromosome
Accession NZ_CP080999
Organism Mycobacterium malmoense strain ATCC 29571

Toxin (Protein)


Gene name novel[antitoxin] Uniprot ID -
Locus tag K3U93_RS20085 Protein ID WP_083011414.1
Coordinates 4383311..4383781 (-) Length 157 a.a.

Antitoxin (Protein)


Gene name novel[toxin] Uniprot ID -
Locus tag K3U93_RS20090 Protein ID WP_071510531.1
Coordinates 4383786..4383974 (-) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Polyketide cyclase/dehydrase

(1-142)

Antitoxin

Antitoxin Rv0909/MT0933

(4-52)


Sequences

Toxin        


Download         Length: 157 a.a.        Molecular weight: 17132.83 Da        Isoelectric Point: 9.5924

>T212425 WP_083011414.1 NZ_CP080999:c4383781-4383311 [Mycobacterium malmoense]
MAKLSGSIDVPLPPEVAWKHASDLSRYREWLTIHRVWRSTLPDEIEKGTVIESIVEVKGMLNRIRWTVVHYKPPQGMTLN
GDGVGGVKVKLMAKIQPKDEGSVVGFDVHLGGPALFGPIGMIVAAALRSDINESLHNFVRVFTAPDPQMNGDGGRR

Download         Length: 471 bp

>T212425 NZ_CP107014:c3289410-3289308 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 6605.29 Da        Isoelectric Point: 5.0336

>AT212425 WP_071510531.1 NZ_CP080999:c4383974-4383786 [Mycobacterium malmoense]
VGFLDKAKDLLAQNADKVETAIDKAGEFVDGKTKGKYSDTIHKVQEEAKKAAESAGPGDQQN

Download         Length: 189 bp

>AT212425 NZ_CP107014:3289301-3289446 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References