Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 2881059..2881744 Replicon chromosome
Accession NZ_CP080999
Organism Mycobacterium malmoense strain ATCC 29571

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag K3U93_RS13415 Protein ID WP_083011068.1
Coordinates 2881059..2881490 (-) Length 144 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag K3U93_RS13420 Protein ID WP_083011067.1
Coordinates 2881487..2881744 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2850011..2882869 32858


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-133)

Antitoxin

Ribbon-helix-helix protein, CopG

(2-36)


Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 15770.86 Da        Isoelectric Point: 4.5713

>T212419 WP_083011068.1 NZ_CP080999:c2881490-2881059 [Mycobacterium malmoense]
MRLLDLNILIYAIDESSSRHVVAKDWLDDTLSGSDTVAFSWHVLIGFVRLSTRAAVFERPLTVDESFDVVDGWLEQPCVT
VVHPTDRHAIVLRGILTPLGTAGNLTSDAHLAALSIEHGAELCSTDVDFSRFSGVRWIDPLQT

Download         Length: 432 bp

>T212419 NZ_CP107011:52897-53049 [Salmonella enterica subsp. enterica serovar Paratyphi B]
ATGCCACAGCGAACGTTTTTAATGATGTTAATCGTCATCTGTGTGACGATTCTGTGTTTTGTCTGGATGGTGAGGGATTC
GCTTTGCGGACTCCGGCTCCAGCAGGGAAACACAGTGCTTGTGGCAACGTTAGCCTACGAAGTTAAACGTTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9348.72 Da        Isoelectric Point: 11.0899

>AT212419 WP_083011067.1 NZ_CP080999:c2881744-2881487 [Mycobacterium malmoense]
MRTTVTLDPDVVAALQRAARERGASFKAVLNDAVRRGLSGGPTQRRYHTPSRDMGLRTGFDIDKALTLVAADEDAEILRK
LALRK

Download         Length: 258 bp

>AT212419 NZ_CP107011:c52842-52785 [Salmonella enterica subsp. enterica serovar Paratyphi B]
GCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References