Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1071081..1071224 Replicon chromosome
Accession NZ_CP080960
Organism Salmonella enterica subsp. enterica serovar Typhi strain ISP2825

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1071120..1071222 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1071081..1071224 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K3U68_RS05010 (K3U68_05010) 1067505..1068203 - 699 WP_000944282.1 exodeoxyribonuclease X -
K3U68_RS05015 (K3U68_05015) 1068227..1068883 - 657 WP_000100250.1 carbon-nitrogen hydrolase family protein -
K3U68_RS05020 (K3U68_05020) 1068991..1069221 - 231 WP_000856224.1 DNA polymerase III subunit theta -
K3U68_RS05025 (K3U68_05025) 1069359..1069733 + 375 WP_001681742.1 CopC domain-containing protein YobA -
K3U68_RS05030 (K3U68_05030) 1069734..1070609 + 876 WP_000979693.1 copper homeostasis membrane protein CopD -
K3U68_RS05035 (K3U68_05035) 1070626..1070979 + 354 WP_000722366.1 YebY family protein -
- 1071081..1071224 - 144 - - Antitoxin
- 1071120..1071222 + 103 - - Toxin
K3U68_RS05040 (K3U68_05040) 1071343..1071651 - 309 Protein_986 tyrosine-type recombinase/integrase -
K3U68_RS05045 (K3U68_05045) 1071650..1072011 - 362 Protein_987 recombinase RecT -
K3U68_RS05050 (K3U68_05050) 1072012..1072122 + 111 Protein_988 replication protein -
K3U68_RS05055 (K3U68_05055) 1072135..1072530 + 396 Protein_989 DUF977 family protein -
K3U68_RS05060 (K3U68_05060) 1072816..1073946 - 1131 WP_000529513.1 GGDEF domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1065417..1071817 6400


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T212374 NZ_CP080960:1071120-1071222 [Salmonella enterica subsp. enterica serovar Typhi]
GCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT212374 NZ_CP080960:c1071224-1071081 [Salmonella enterica subsp. enterica serovar Typhi]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References