Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1384961..1385195 Replicon chromosome
Accession NC_007384
Organism Shigella sonnei Ss046

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1385091..1385194 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1384961..1385195 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SSON_RS07170 1381516..1382178 - 663 WP_000944256.1 exodeoxyribonuclease X -
SSON_RS07175 1382202..1382858 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
SSON_RS07180 1382960..1383190 - 231 WP_000916763.1 DNA polymerase III subunit theta -
SSON_RS07185 1383329..1383703 + 375 WP_000168735.1 CopC domain-containing protein YobA -
SSON_RS07190 1383707..1384579 + 873 WP_000879296.1 copper homeostasis membrane protein CopD -
SSON_RS07195 1384592..1384933 + 342 WP_000976476.1 YebY family protein -
- 1384961..1385195 - 235 - - Antitoxin
- 1385091..1385194 + 104 - - Toxin
SSON_RS07205 1385326..1386402 - 1077 WP_001189101.1 phage integrase Arm DNA-binding domain-containing protein -
SSON_RS07210 1386439..1386684 - 246 Protein_1347 IS1 family transposase -
SSON_RS30970 1387973..1388427 - 455 Protein_1349 IS1-like element IS1A family transposase -
SSON_RS27845 1388456..1388716 - 261 WP_077447296.1 excisionase -
SSON_RS07240 1388861..1390017 + 1157 WP_087879964.1 IS3-like element IS600 family transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - ipaH9.8 1379459..1412112 32653


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T21236 NC_007384:1385091-1385194 [Shigella sonnei Ss046]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT21236 NC_007384:c1385195-1384961 [Shigella sonnei Ss046]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References