Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 1956950..1957494 Replicon chromosome
Accession NZ_CP080633
Organism Shewanella putrefaciens strain YZ08

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag K2227_RS08765 Protein ID WP_220592667.1
Coordinates 1957195..1957494 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K2227_RS08760 Protein ID WP_220592666.1
Coordinates 1956950..1957207 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K2227_RS08735 (K2227_08735) 1953358..1953795 + 438 WP_220592661.1 GNAT family N-acetyltransferase -
K2227_RS08740 (K2227_08740) 1953882..1954535 + 654 WP_220592662.1 hypothetical protein -
K2227_RS08745 (K2227_08745) 1954634..1954867 + 234 WP_220592663.1 hypothetical protein -
K2227_RS08750 (K2227_08750) 1955898..1956341 + 444 WP_220592664.1 hypothetical protein -
K2227_RS08755 (K2227_08755) 1956444..1956800 + 357 WP_220592665.1 hypothetical protein -
K2227_RS08760 (K2227_08760) 1956950..1957207 + 258 WP_220592666.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
K2227_RS08765 (K2227_08765) 1957195..1957494 + 300 WP_220592667.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K2227_RS08770 (K2227_08770) 1957574..1957981 + 408 WP_220592668.1 hypothetical protein -
K2227_RS08775 (K2227_08775) 1958070..1958489 + 420 WP_220592669.1 hypothetical protein -
K2227_RS08780 (K2227_08780) 1958708..1959472 + 765 WP_220592670.1 SDR family oxidoreductase -
K2227_RS08785 (K2227_08785) 1959484..1960326 + 843 WP_220592671.1 methylated-DNA--[protein]-cysteine S-methyltransferase -
K2227_RS08790 (K2227_08790) 1960425..1961009 + 585 WP_220592672.1 DUF6151 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11485.22 Da        Isoelectric Point: 4.3543

>T212320 WP_220592667.1 NZ_CP080633:1957195-1957494 [Shewanella putrefaciens]
MAEVIWTEPALQELDAIAEYIALDNPAAASDLVKAVFDKTERLENFPKSGRIPPELPDSVYREVVIPPCRIFYREDEQRV
FVLFVMREERQLRAFMLGN

Download         Length: 300 bp

>T212320 NZ_CP107002:2671044-2671151 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9813.38 Da        Isoelectric Point: 9.5353

>AT212320 WP_220592666.1 NZ_CP080633:1956950-1957207 [Shewanella putrefaciens]
MKVELVTNLKRQATKILADLHLSKEPVLITEHGQPSAYLVDVQDYEFMQRRLALLEGLARGERAVLEGRTYSQSEARDKM
TKWLK

Download         Length: 258 bp

>AT212320 NZ_CP107002:c2670997-2670931 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References