212319

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ygfYX/Cpta(toxin)
Location 1401649..1402318 Replicon chromosome
Accession NZ_CP080633
Organism Shewanella putrefaciens strain YZ08

Toxin (Protein)


Gene name ygfX Uniprot ID -
Locus tag K2227_RS06245 Protein ID WP_220592330.1
Coordinates 1401878..1402318 (+) Length 147 a.a.

Antitoxin (Protein)


Gene name ygfY Uniprot ID -
Locus tag K2227_RS06240 Protein ID WP_106649849.1
Coordinates 1401649..1401897 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K2227_RS06215 (K2227_06215) 1397306..1398115 + 810 WP_220592327.1 prolipoprotein diacylglyceryl transferase -
K2227_RS06220 (K2227_06220) 1398112..1398906 + 795 WP_220592328.1 thymidylate synthase -
K2227_RS06225 (K2227_06225) 1399024..1400193 + 1170 WP_106649846.1 Na+/H+ antiporter NhaA -
K2227_RS06230 (K2227_06230) 1400196..1400582 + 387 WP_220592329.1 hypothetical protein -
K2227_RS06235 (K2227_06235) 1400655..1401563 + 909 WP_063884532.1 transcriptional activator NhaR -
K2227_RS06240 (K2227_06240) 1401649..1401897 + 249 WP_106649849.1 succinate dehydrogenase assembly factor 2 Antitoxin
K2227_RS06245 (K2227_06245) 1401878..1402318 + 441 WP_220592330.1 protein YgfX Toxin
K2227_RS06250 (K2227_06250) 1402370..1403983 - 1614 WP_168823426.1 L-aspartate oxidase -
K2227_RS06255 (K2227_06255) 1404173..1404751 + 579 WP_106649852.1 RNA polymerase sigma factor RpoE -
K2227_RS06260 (K2227_06260) 1404793..1405407 + 615 WP_220592331.1 RseA family anti-sigma factor -
K2227_RS06265 (K2227_06265) 1405420..1406352 + 933 WP_220592332.1 MucB/RseB C-terminal domain-containing protein -
K2227_RS06270 (K2227_06270) 1406363..1406833 + 471 WP_220592333.1 SoxR reducing system RseC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(6-135)

Antitoxin

Flavinator of succinate dehydrogenase

(7-77)


Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 17314.36 Da        Isoelectric Point: 8.3618

>T212319 WP_220592330.1 NZ_CP080633:1401878-1402318 [Shewanella putrefaciens]
VEDRHHSFSVKASFDQRLSLVVFICVCSSSFLFWPQSDNFALSLLKYLFIALVCIFLLSQLWRLQQWRLDFVLSDKGEGR
LSTGEHFKVLKRTWVTPFVCLMYIEVDTQLRLLMVWADMLDDTDYRHLCRLLLRAKIKQTKPHNEV

Download         Length: 441 bp

>T212319 NZ_CP107002:2670509-2670616 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9767.41 Da        Isoelectric Point: 4.4929

>AT212319 WP_106649849.1 NZ_CP080633:1401649-1401897 [Shewanella putrefaciens]
MELMNIARVRWACRRGMLELDVLFQPFVENFYQEMSDEDKTVFIRLLECEDPELFAWFMGHEVCPDTELARMIVKVRGRP
AP

Download         Length: 249 bp

>AT212319 NZ_CP107002:c2670462-2670396 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References