Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 806150..806697 Replicon chromosome
Accession NZ_CP080627
Organism Halomonas qaidamensis strain XH36

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag K1Y77_RS03785 Protein ID WP_264430410.1
Coordinates 806150..806449 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag K1Y77_RS03790 Protein ID WP_162218123.1
Coordinates 806449..806697 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K1Y77_RS03760 (K1Y77_03755) 801644..803221 + 1578 WP_264018747.1 glutamine-hydrolyzing GMP synthase -
K1Y77_RS03765 803277..803336 + 60 WP_264431415.1 type I toxin-antitoxin system ptaRNA1 family toxin -
K1Y77_RS03770 (K1Y77_03765) 803395..803748 + 354 Protein_723 conjugal transfer transcriptional regulator TraJ -
K1Y77_RS03775 (K1Y77_03770) 803804..805498 - 1695 WP_264018746.1 LA2681 family HEPN domain-containing protein -
K1Y77_RS03780 (K1Y77_03775) 805795..805959 - 165 WP_264430409.1 hypothetical protein -
K1Y77_RS03785 (K1Y77_03780) 806150..806449 - 300 WP_264430410.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K1Y77_RS03790 (K1Y77_03785) 806449..806697 - 249 WP_162218123.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
K1Y77_RS03795 (K1Y77_03790) 806972..807301 + 330 WP_264430413.1 virulence RhuM family protein -
K1Y77_RS03800 (K1Y77_03795) 807368..807844 + 477 WP_030069799.1 NYN domain-containing protein -
K1Y77_RS03805 (K1Y77_03800) 807870..808166 - 297 WP_030069802.1 DUF1330 domain-containing protein -
K1Y77_RS03810 (K1Y77_03805) 808391..809590 + 1200 WP_264430415.1 multidrug effflux MFS transporter -
K1Y77_RS03815 (K1Y77_03810) 809669..810460 + 792 WP_264430417.1 PhzF family phenazine biosynthesis protein -
K1Y77_RS03820 (K1Y77_03815) 810491..811018 - 528 WP_264430418.1 hypothetical protein -
K1Y77_RS03825 (K1Y77_03820) 811107..811550 - 444 WP_030069810.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-91)

Antitoxin

Antitoxin ParD

(3-81)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11932.54 Da        Isoelectric Point: 7.4167

>T212305 WP_264430410.1 NZ_CP080627:c806449-806150 [Halomonas qaidamensis]
MPTFHITLRARDDLKNIGRYTEWQWGKNQRNTYLKNFEKRFHWLAENPQLGKHRSDVSEGYYSYPQGQHVIFYLIGQECI
EIIGIPHKEMDIVSYFLPE

Download         Length: 300 bp

>T212305 NZ_CP107002:c605876-605412 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTCTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGAGAAACAGAAGAAACCCATTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9058.01 Da        Isoelectric Point: 4.3875

>AT212305 WP_162218123.1 NZ_CP080627:c806697-806449 [Halomonas qaidamensis]
MATTSLSLGEHWEVFIRNEVASGRYGSASEVVRDALRAMEERKSKLEALRTHLAQGAEQARAGEFVDDFSMDALINDLDS
EA

Download         Length: 249 bp

>AT212305 NZ_CP107002:c606211-605876 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTATTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References