Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 2944658..2945241 Replicon chromosome
Accession NZ_CP080624
Organism Acidiferrobacter thiooxydans strain ZJ

Toxin (Protein)


Gene name vapC Uniprot ID A0A1C2G4F6
Locus tag A9R16_RS13820 Protein ID WP_065968798.1
Coordinates 2944658..2945038 (-) Length 127 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A1C2G4H5
Locus tag A9R16_RS13825 Protein ID WP_065968799.1
Coordinates 2945035..2945241 (-) Length 69 a.a.

Genomic Context

A9R16_RS13805A9R16_RS13810A9R16_RS13815A9R16_RS13800A9R16_RS13820A9R16_RS13825A9R16_RS13830A9R16_RS13835
Location: 2942696..2943205 (510 bp)
Type: Others
Protein ID: WP_065968797.1
Location: 2943220..2944326 (1107 bp)
Type: Others
Protein ID: WP_211306971.1
Location: 2944387..2944530 (144 bp)
Type: Others
Protein ID: WP_170132546.1
Location: 2940794..2942539 (1746 bp)
Type: Others
Protein ID: WP_065972275.1
Location: 2944658..2945038 (381 bp)
Type: Toxin
Protein ID: WP_065968798.1
Location: 2945035..2945241 (207 bp)
Type: Antitoxin
Protein ID: WP_065968799.1
Location: 2945929..2946336 (408 bp)
Type: Others
Protein ID: WP_065968801.1
Location: 2946333..2948651 (2319 bp)
Type: Others
Protein ID: WP_065968802.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
A9R16_RS13800 (A9R16_013960)2940794..2942539-1746WP_065972275.1IS1634 family transposase-
A9R16_RS13805 (A9R16_013965)2942696..2943205+510WP_065968797.1hypothetical protein-
A9R16_RS13810 (A9R16_013970)2943220..2944326+1107WP_211306971.1tellurite resistance/C4-dicarboxylate transporter family protein-
A9R16_RS13815 (A9R16_013975)2944387..2944530+144WP_170132546.1hypothetical protein-
A9R16_RS13820 (A9R16_013980)2944658..2945038-381WP_065968798.1PIN domain-containing proteinToxin
A9R16_RS13825 (A9R16_013985)2945035..2945241-207WP_065968799.1antitoxin of toxin-antitoxin stability systemAntitoxin
A9R16_RS13830 (A9R16_013990)2945929..2946336-408WP_065968801.1hypothetical protein-
A9R16_RS13835 (A9R16_013995)2946333..2948651-2319WP_065968802.1cbb3-type cytochrome c oxidase subunit I-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-110)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 127 a.a.        Molecular weight: 13971.27 Da        Isoelectric Point: 5.1293

>T212299 WP_065968798.1 NZ_CP080624:c2945038-2944658 [Acidiferrobacter thiooxydans]
MSVLVDTSVWVDHFRNRNDVLVRLIEADMALTHPMVVAELACGTPPAPRTQTLGDIDLLRPCNQASLAEVRDFIEREKLY
GLGCGLVDIALLTSALLTSGASLWTLDKRLMGLAERFEVVYRPLPH

Download         Length: 381 bp

>T212299 NZ_CP107001:c3753913-3753515 [Escherichia coli]
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAACTTGATGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGCGATGCACTCTACGACGACTCCTTTACCTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGAGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGAAGCGCATTTGGTATATTGTCAGGGGGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACTGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7565.66 Da        Isoelectric Point: 6.2807

>AT212299 WP_065968799.1 NZ_CP080624:c2945241-2945035 [Acidiferrobacter thiooxydans]
MRTTVTIDDAIYQKALEMADPNMDRADIFREAMKTYVRVQAAKRLAALGGAAPDMQDVPRRREEPAAG

Download         Length: 207 bp

>AT212299 NZ_CP107001:c3754209-3753916 [Escherichia coli]
ATGCATCGAATTCTCGCTGAAAAATCGGTCAATATCACTGAGTTACGTAAAAACCCAGCTAAATACTTTATTGATCAACC
GGTTGCGGTTCTTTCTAATAATCGCCCCGCAGGATATCTCTTAAGTGCCAGCGCATTCGAAGCGTTAATGGACATGCTTG
CTGAACAAGAGGAGAAAAAGCCCATAAAGGCGCGCTTCCGTCCAAGTGCTGCAAGATTAGAGGAAATTACACGCCGCGCT
GAACAATATCTTAATGATATGACGGATGATGATTTCAATGACTTTAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A1C2G4F6

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A1C2G4H5

References