Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 413888..414581 Replicon chromosome
Accession NZ_CP080624
Organism Acidiferrobacter thiooxydans strain ZJ

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag A9R16_RS02050 Protein ID WP_083995678.1
Coordinates 413888..414226 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag A9R16_RS02055 Protein ID WP_228579807.1
Coordinates 414312..414581 (-) Length 90 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A9R16_RS02045 (A9R16_002060) 411838..413301 + 1464 WP_176715931.1 ShlB/FhaC/HecB family hemolysin secretion/activation protein -
A9R16_RS02050 (A9R16_002065) 413888..414226 - 339 WP_083995678.1 VapC toxin family PIN domain ribonuclease Toxin
A9R16_RS02055 (A9R16_002070) 414312..414581 - 270 WP_228579807.1 hypothetical protein Antitoxin
A9R16_RS15405 415156..415284 + 129 WP_267254315.1 hypothetical protein -
A9R16_RS02060 (A9R16_002080) 415598..416578 - 981 WP_065969245.1 alpha-E domain-containing protein -
A9R16_RS02065 (A9R16_002085) 416780..418204 - 1425 WP_228579809.1 circularly permuted type 2 ATP-grasp protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-111)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 113 a.a.        Molecular weight: 12432.33 Da        Isoelectric Point: 7.4784

>T212296 WP_083995678.1 NZ_CP080624:c414226-413888 [Acidiferrobacter thiooxydans]
MRGDQSISLPWVVILAFLRVTTNARVFEQPLPVERASAYIQEWLSLPTVRAVVPGHGHWAIWHILLVQRGTCGNLTTDAH
IAALALEHGYTIYCPDHGFGRFGGARHVDPLP

Download         Length: 339 bp

>T212296 NZ_CP107001:2671044-2671151 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9722.39 Da        Isoelectric Point: 10.3120

>AT212296 WP_228579807.1 NZ_CP080624:c414581-414312 [Acidiferrobacter thiooxydans]
MMRTTLTIDEKVGAALQETARRMKKPYKAVVNEALRLGLHAMAHPSARAYHLVPSALGDVRTGLNLDKAPAIAEALEDDA
TAQKLMLRK

Download         Length: 270 bp

>AT212296 NZ_CP107001:c2670997-2670931 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References