Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/PIN(toxin) |
| Location | 413888..414581 | Replicon | chromosome |
| Accession | NZ_CP080624 | ||
| Organism | Acidiferrobacter thiooxydans strain ZJ | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | A9R16_RS02050 | Protein ID | WP_083995678.1 |
| Coordinates | 413888..414226 (-) | Length | 113 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | A9R16_RS02055 | Protein ID | WP_228579807.1 |
| Coordinates | 414312..414581 (-) | Length | 90 a.a. |
Genomic Context
Location: 411838..413301 (1464 bp)
Type: Others
Protein ID: WP_176715931.1
Type: Others
Protein ID: WP_176715931.1
Location: 415156..415284 (129 bp)
Type: Others
Protein ID: WP_267254315.1
Type: Others
Protein ID: WP_267254315.1
Location: 413888..414226 (339 bp)
Type: Toxin
Protein ID: WP_083995678.1
Type: Toxin
Protein ID: WP_083995678.1
Location: 414312..414581 (270 bp)
Type: Antitoxin
Protein ID: WP_228579807.1
Type: Antitoxin
Protein ID: WP_228579807.1
Location: 415598..416578 (981 bp)
Type: Others
Protein ID: WP_065969245.1
Type: Others
Protein ID: WP_065969245.1
Location: 416780..418204 (1425 bp)
Type: Others
Protein ID: WP_228579809.1
Type: Others
Protein ID: WP_228579809.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A9R16_RS02045 (A9R16_002060) | 411838..413301 | + | 1464 | WP_176715931.1 | ShlB/FhaC/HecB family hemolysin secretion/activation protein | - |
| A9R16_RS02050 (A9R16_002065) | 413888..414226 | - | 339 | WP_083995678.1 | VapC toxin family PIN domain ribonuclease | Toxin |
| A9R16_RS02055 (A9R16_002070) | 414312..414581 | - | 270 | WP_228579807.1 | hypothetical protein | Antitoxin |
| A9R16_RS15405 | 415156..415284 | + | 129 | WP_267254315.1 | hypothetical protein | - |
| A9R16_RS02060 (A9R16_002080) | 415598..416578 | - | 981 | WP_065969245.1 | alpha-E domain-containing protein | - |
| A9R16_RS02065 (A9R16_002085) | 416780..418204 | - | 1425 | WP_228579809.1 | circularly permuted type 2 ATP-grasp protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 113 a.a. Molecular weight: 12432.33 Da Isoelectric Point: 7.4784
>T212296 WP_083995678.1 NZ_CP080624:c414226-413888 [Acidiferrobacter thiooxydans]
MRGDQSISLPWVVILAFLRVTTNARVFEQPLPVERASAYIQEWLSLPTVRAVVPGHGHWAIWHILLVQRGTCGNLTTDAH
IAALALEHGYTIYCPDHGFGRFGGARHVDPLP
MRGDQSISLPWVVILAFLRVTTNARVFEQPLPVERASAYIQEWLSLPTVRAVVPGHGHWAIWHILLVQRGTCGNLTTDAH
IAALALEHGYTIYCPDHGFGRFGGARHVDPLP
Download Length: 339 bp
>T212296 NZ_CP107001:2671044-2671151 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 90 a.a. Molecular weight: 9722.39 Da Isoelectric Point: 10.3120
>AT212296 WP_228579807.1 NZ_CP080624:c414581-414312 [Acidiferrobacter thiooxydans]
MMRTTLTIDEKVGAALQETARRMKKPYKAVVNEALRLGLHAMAHPSARAYHLVPSALGDVRTGLNLDKAPAIAEALEDDA
TAQKLMLRK
MMRTTLTIDEKVGAALQETARRMKKPYKAVVNEALRLGLHAMAHPSARAYHLVPSALGDVRTGLNLDKAPAIAEALEDDA
TAQKLMLRK
Download Length: 270 bp
>AT212296 NZ_CP107001:c2670997-2670931 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT