Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2773187..2773458 Replicon chromosome
Accession NZ_CP080620
Organism Escherichia coli strain TOP10

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2773317..2773420 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2773187..2773458 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K3F56_RS13215 2769742..2770404 - 663 WP_000944256.1 exodeoxyribonuclease X -
K3F56_RS13220 2770428..2771084 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
K3F56_RS13225 2771186..2771416 - 231 WP_000916763.1 DNA polymerase III subunit theta -
K3F56_RS13230 2771555..2771929 + 375 WP_000168747.1 CopC domain-containing protein YobA -
K3F56_RS13235 2771933..2772805 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
K3F56_RS13240 2772818..2773159 + 342 WP_000976476.1 YebY family protein -
- 2773187..2773458 - 272 - - Antitoxin
- 2773317..2773420 + 104 - - Toxin
K3F56_RS13245 2773555..2774211 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
K3F56_RS13250 2774212..2774403 - 192 WP_000457842.1 YebW family protein -
K3F56_RS13255 2774508..2774744 - 237 WP_001295499.1 YebV family protein -
K3F56_RS13260 2774862..2776301 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T212274 NZ_CP080620:2773317-2773420 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT212274 NZ_CP080620:c2773458-2773187 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References