Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2533166..2533334 Replicon chromosome
Accession NZ_CP080591
Organism Cronobacter sakazakii strain Crono-589

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2533169..2533272 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2533166..2533334 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K1721_RS11930 (K1721_11905) 2528545..2529987 + 1443 WP_032989335.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
K1721_RS11935 (K1721_11910) 2530099..2530338 + 240 WP_004386676.1 YebV family protein -
K1721_RS11940 (K1721_11915) 2530463..2530654 + 192 WP_004386675.1 YebW family protein -
K1721_RS11945 (K1721_11920) 2530655..2531299 - 645 WP_032989334.1 metallophosphoesterase -
K1721_RS11950 (K1721_11930) 2531657..2531749 - 93 WP_004386672.1 hypothetical protein -
K1721_RS11955 (K1721_11935) 2532095..2532430 - 336 WP_004386671.1 hypothetical protein -
K1721_RS11960 (K1721_11940) 2532384..2532944 - 561 WP_032989333.1 hypothetical protein -
- 2533166..2533334 + 169 - - Antitoxin
- 2533169..2533272 - 104 - - Toxin
K1721_RS11965 (K1721_11945) 2533411..2533749 - 339 WP_004386669.1 YebY family protein -
K1721_RS11970 (K1721_11950) 2533764..2534633 - 870 WP_032989331.1 copper homeostasis membrane protein CopD -
K1721_RS11975 (K1721_11955) 2534638..2535012 - 375 WP_032989330.1 CopC domain-containing protein YobA -
K1721_RS11980 (K1721_11960) 2535159..2535389 + 231 WP_007698883.1 DNA polymerase III subunit theta -
K1721_RS11985 (K1721_11965) 2535461..2536123 + 663 WP_004386664.1 exodeoxyribonuclease X -
K1721_RS11990 (K1721_11970) 2536120..2538183 - 2064 WP_004386663.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T212226 NZ_CP080591:c2533272-2533169 [Cronobacter sakazakii]
GGCAAGGCGACTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 169 bp

>AT212226 NZ_CP080591:2533166-2533334 [Cronobacter sakazakii]
GATAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGG
CATTAATGCAGGCTCAGTCGCCTTGCCTTTTAAGAATAGATGACGACACCAGCTTTTCCAGTTTGCGGCTAAAGTCGCAG
CAAAAAGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References