Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) NpoTA/ParE(toxin)
Location 257111..258301 Replicon chromosome
Accession NZ_CP080590
Organism Devosia salina strain SCS-3

Toxin (Protein)


Gene name NpoT Uniprot ID -
Locus tag K1X15_RS01290 Protein ID WP_220305720.1
Coordinates 257984..258301 (-) Length 106 a.a.

Antitoxin (Protein)


Gene name NpoA Uniprot ID -
Locus tag K1X15_RS01285 Protein ID WP_240549618.1
Coordinates 257111..257974 (-) Length 288 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K1X15_RS01270 (K1X15_01270) 252924..254240 + 1317 WP_220305717.1 hypothetical protein -
K1X15_RS01275 (K1X15_01275) 254216..255208 - 993 WP_220305718.1 heparan-alpha-glucosaminide N-acetyltransferase -
K1X15_RS01280 (K1X15_01280) 255205..257061 - 1857 WP_220305719.1 DNA helicase RecQ -
K1X15_RS01285 (K1X15_01285) 257111..257974 - 864 WP_240549618.1 SDR family oxidoreductase Antitoxin
K1X15_RS01290 (K1X15_01290) 257984..258301 - 318 WP_220305720.1 plasmid stabilization protein Toxin
K1X15_RS01295 (K1X15_01295) 258486..259061 - 576 WP_276315286.1 DNA-3-methyladenine glycosylase -
K1X15_RS01300 (K1X15_01300) 259227..260150 + 924 WP_220305721.1 VOC family protein -
K1X15_RS01305 (K1X15_01305) 260209..260754 + 546 WP_220305722.1 DUF924 family protein -
K1X15_RS01310 (K1X15_01310) 260813..260986 + 174 WP_220305723.1 hypothetical protein -
K1X15_RS01315 (K1X15_01315) 261021..262817 - 1797 WP_220305724.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11471.44 Da        Isoelectric Point: 10.7054

>T212220 WP_220305720.1 NZ_CP080590:c258301-257984 [Devosia salina]
MPQGDKSAYTDKQKRKAEHIEERYEDRGVSHKEAERRAWATVNKDDGGGNKSGSGRGTHKDHPAAHKGGKKGGEASANRP
ASERSASAKKAAATRKRNQEHHAHH

Download         Length: 318 bp

>T212220 NZ_CP106998:2247036-2247323 [Escherichia coli]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA

Antitoxin


Download         Length: 288 a.a.        Molecular weight: 30541.63 Da        Isoelectric Point: 5.3996

>AT212220 WP_240549618.1 NZ_CP080590:c257974-257111 [Devosia salina]
MSGSAAKPMNPPQTQDHQPGRESEMHPKPDYMPKFPGNGRLKDKVAIITGGDSGIGRACAVLFAREGAEVALVYLEETDD
ARLTAEAVKAEGKEALLLRGDVSDKAVCESVVGQVVEKFGKLDVLVNNAAEQHMQTELEAISEEQLRRTFETNFFGYMFM
TQAALPHLRKGSAIVNTTSITAYRGSPSLMDYAATKGAIVAFTRSLSESLAGKGIRVNGVAPGPIWTPLIPASFPADKVA
EFGASQPLGRPGQPNEVATSHLFLACEESSYITGQVLHPNGGEIIGG

Download         Length: 864 bp

>AT212220 NZ_CP106998:2246797-2247036 [Escherichia coli]
ATGGGTAGCATTAACCTGCGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGTGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGGCTTCGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References