212214

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 402677..403038 Replicon chromosome
Accession NZ_CP080589
Organism Xanthomonas oryzae pv. oryzicola strain GX01

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag K2I41_RS02060 Protein ID WP_011257368.1
Coordinates 402904..403038 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag K2I41_RS02055 Protein ID WP_011407410.1
Coordinates 402677..402829 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K2I41_RS02030 (K2I41_02035) 399021..399704 - 684 WP_014505034.1 dTMP kinase -
K2I41_RS02035 (K2I41_02040) 400184..400719 - 536 Protein_333 GTPase -
K2I41_RS02040 (K2I41_02045) 400716..401114 - 399 Protein_334 hypothetical protein -
K2I41_RS02045 401106..401324 - 219 Protein_335 hypothetical protein -
K2I41_RS02050 (K2I41_02050) 401646..402569 + 924 WP_014505030.1 arginase -
K2I41_RS02055 (K2I41_02055) 402677..402829 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
K2I41_RS02060 (K2I41_02060) 402904..403038 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
K2I41_RS02065 (K2I41_02065) 403281..403490 + 210 WP_011407411.1 CsbD family protein -
K2I41_RS02070 (K2I41_02070) 403659..404948 + 1290 WP_024711517.1 tryptophan--tRNA ligase -
K2I41_RS02075 (K2I41_02075) 405079..406023 + 945 WP_044749698.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T212214 WP_011257368.1 NZ_CP080589:402904-403038 [Xanthomonas oryzae pv. oryzicola]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T212214 NZ_CP106998:c1111740-1111411 [Escherichia coli]
ATGAACACTCTACCTGCTACAATTTCGCAGGCGGCGAAGCCCTGCCTGTCGCCAGTGGCTGTCTGGCAAATGCTACTGAC
ACGCCTGCTGGAACAACACTATGGCCTGACACTGAACGACACGCCGTTCAGTGATGAAACTGTTATTAAGGAACATATCG
ATGCTGGTATCACTCTGGCCGATGCAGTCAATTTTCTGGTGGAAAAGTACGAACTGGTACGTATCGATCACAGAGGATTT
TCGTGGCAACAACAGTCTCCATATATTTCCGTAGTAGATATTCTGCGAGCAAGGCGCTCTACCGGCTTGCTAAAAACTAA
TGTGAAATAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT212214 WP_011407410.1 NZ_CP080589:402677-402829 [Xanthomonas oryzae pv. oryzicola]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT212214 NZ_CP106998:c1112078-1111761 [Escherichia coli]
ATGAGCAACACCACATGGGGCCTGCAGCGAGATATCACGCCGCGCCTGGGAGCACGTCTGGTGCAGGAGGGCAACCAGCT
GCACTATCTGGCTGACCGGGCCAGTATCACCGGTAAGTTTAGTGACGCCGAATGTCCTAAGCTGGATGTGGTATTTCCAC
ATTTTATCAGCCAGATAGAGTCGATGCTGACCACTGGTGAACTGAATCCCCGCCATGCCCAATGCGTCACCCTGTACCAC
AACGGTTTTACCTGCGAAGCCGATACTCTTGGTAGTTGCGGCTACGTATACATCGCTGTTTACCCCACTCAACGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References