Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 59577..60046 Replicon plasmid largeplasmid
Accession NC_007274
Organism Pseudomonas syringae pv. phaseolicola 1448A

Toxin (Protein)


Gene name relE Uniprot ID Q48BA0
Locus tag PSPPH_RS26795 Protein ID WP_002556029.1
Coordinates 59765..60046 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q48BA1
Locus tag PSPPH_RS26790 Protein ID WP_002556028.1
Coordinates 59577..59765 (+) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSPPH_RS26775 55181..55630 + 450 WP_011282491.1 invasin protein AfaD -
PSPPH_RS29680 55705..56265 + 561 WP_054073162.1 hypothetical protein -
PSPPH_RS26780 57374..58477 + 1104 WP_011282424.1 IS5-like element ISPsy19 family transposase -
PSPPH_RS26785 58764..59399 + 636 WP_011282469.1 recombinase family protein -
PSPPH_RS26790 59577..59765 + 189 WP_002556028.1 hypothetical protein Antitoxin
PSPPH_RS26795 59765..60046 + 282 WP_002556029.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PSPPH_RS26800 60198..61745 - 1548 WP_041924905.1 glycoside hydrolase family 28 protein -
PSPPH_RS26805 61829..62053 - 225 WP_041924893.1 carbon storage regulator -
PSPPH_RS26810 62157..62339 - 183 WP_004661237.1 hypothetical protein -
PSPPH_RS29695 62769..63083 - 315 WP_081002620.1 hypothetical protein -
PSPPH_RS29700 63182..63466 - 285 WP_011282457.1 type III effector HopW1-1, truncated -
PSPPH_RS26820 63629..63904 - 276 Protein_70 recombinase family protein -
PSPPH_RS26825 64354..64803 - 450 WP_005760341.1 type II toxin-antitoxin system PemK/MazF family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..131950 131950
- flank IS/Tn - - 57374..58477 1103


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10675.35 Da        Isoelectric Point: 8.4392

>T21219 WP_002556029.1 NC_007274:59765-60046 [Pseudomonas savastanoi pv. phaseolicola 1448A]
MLPVVWLSPALDDLREIATYIAWENPSAARRLKSLLQEAIEPVAEHPYLYRSGRAPGTRELVAHPNYVLVYRVTLKRIEV
VNVIHARQEYPSP

Download         Length: 282 bp

>T21219 NC_007274:59765-60046 [Pseudomonas savastanoi pv. phaseolicola 1448A]
ATGCTGCCGGTGGTCTGGCTCAGTCCCGCACTGGATGATCTGCGCGAAATCGCAACCTACATCGCATGGGAAAACCCGAG
CGCAGCGCGCCGGTTGAAAAGCCTCCTGCAGGAGGCTATCGAGCCGGTAGCCGAACACCCCTATTTATATCGTTCTGGGC
GAGCGCCAGGCACTCGCGAGCTGGTGGCTCACCCAAACTACGTCTTGGTCTATCGTGTCACCCTCAAGCGCATCGAGGTC
GTGAACGTAATCCACGCTAGGCAGGAATACCCCTCTCCCTGA

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 7043.86 Da        Isoelectric Point: 4.2550

>AT21219 WP_002556028.1 NC_007274:59577-59765 [Pseudomonas savastanoi pv. phaseolicola 1448A]
MANLSPIVSEFETDEQAASYDRWFRAKVAASLADPRPAIPHDEVMAEIEALIDQVETQREKR

Download         Length: 189 bp

>AT21219 NC_007274:59577-59765 [Pseudomonas savastanoi pv. phaseolicola 1448A]
ATGGCCAACCTCTCACCCATCGTTTCAGAATTCGAAACCGATGAACAGGCCGCAAGCTACGACCGCTGGTTTCGCGCCAA
GGTCGCCGCCAGTCTGGCCGATCCGCGTCCGGCCATCCCTCATGATGAGGTCATGGCGGAAATAGAAGCGCTGATCGATC
AGGTTGAAACCCAACGTGAGAAACGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0M9HVA1

Antitoxin

Source ID Structure
AlphaFold DB A0A2G9KWB9

References