Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2807..3276 Replicon plasmid largeplasmid
Accession NC_007274
Organism Pseudomonas syringae pv. phaseolicola 1448A

Toxin (Protein)


Gene name relE Uniprot ID Q48BA0
Locus tag PSPPH_RS26510 Protein ID WP_002556029.1
Coordinates 2995..3276 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q48BA1
Locus tag PSPPH_RS26505 Protein ID WP_002556028.1
Coordinates 2807..2995 (+) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSPPH_RS26495 304..1617 + 1314 WP_032489053.1 replication initiation protein -
PSPPH_RS26500 1747..2627 - 881 Protein_1 transposase -
PSPPH_RS26505 2807..2995 + 189 WP_002556028.1 hypothetical protein Antitoxin
PSPPH_RS26510 2995..3276 + 282 WP_002556029.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PSPPH_RS26515 3428..4975 - 1548 WP_041924905.1 glycoside hydrolase family 28 protein -
PSPPH_RS26520 5059..5283 - 225 WP_041924893.1 carbon storage regulator -
PSPPH_RS26525 5387..5569 - 183 WP_004661237.1 hypothetical protein -
PSPPH_RS29585 5999..6313 - 315 WP_081002620.1 hypothetical protein -
PSPPH_RS29590 6412..6696 - 285 WP_011282457.1 type III effector HopW1-1, truncated -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..131950 131950
- flank IS/Tn - - 1723..2325 602


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10675.35 Da        Isoelectric Point: 8.4392

>T21217 WP_002556029.1 NC_007274:2995-3276 [Pseudomonas savastanoi pv. phaseolicola 1448A]
MLPVVWLSPALDDLREIATYIAWENPSAARRLKSLLQEAIEPVAEHPYLYRSGRAPGTRELVAHPNYVLVYRVTLKRIEV
VNVIHARQEYPSP

Download         Length: 282 bp

>T21217 NC_007274:2995-3276 [Pseudomonas savastanoi pv. phaseolicola 1448A]
ATGCTGCCGGTGGTCTGGCTCAGTCCCGCACTGGATGATCTGCGCGAAATCGCAACCTACATCGCATGGGAAAACCCGAG
CGCAGCGCGCCGGTTGAAAAGCCTCCTGCAGGAGGCTATCGAGCCGGTAGCCGAACACCCCTATTTATATCGTTCTGGGC
GAGCGCCAGGCACTCGCGAGCTGGTGGCTCACCCAAACTACGTCTTGGTCTATCGTGTCACCCTCAAGCGCATCGAGGTC
GTGAACGTAATCCACGCTAGGCAGGAATACCCCTCTCCCTGA

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 7043.86 Da        Isoelectric Point: 4.2550

>AT21217 WP_002556028.1 NC_007274:2807-2995 [Pseudomonas savastanoi pv. phaseolicola 1448A]
MANLSPIVSEFETDEQAASYDRWFRAKVAASLADPRPAIPHDEVMAEIEALIDQVETQREKR

Download         Length: 189 bp

>AT21217 NC_007274:2807-2995 [Pseudomonas savastanoi pv. phaseolicola 1448A]
ATGGCCAACCTCTCACCCATCGTTTCAGAATTCGAAACCGATGAACAGGCCGCAAGCTACGACCGCTGGTTTCGCGCCAA
GGTCGCCGCCAGTCTGGCCGATCCGCGTCCGGCCATCCCTCATGATGAGGTCATGGCGGAAATAGAAGCGCTGATCGATC
AGGTTGAAACCCAACGTGAGAAACGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0M9HVA1

Antitoxin

Source ID Structure
AlphaFold DB A0A2G9KWB9

References