Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 5626581..5627242 Replicon chromosome
Accession NZ_CP080531
Organism Mesorhizobium sp. AR02

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag DBIPINDM_RS31405 Protein ID WP_258582844.1
Coordinates 5626805..5627242 (+) Length 146 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag DBIPINDM_RS31400 Protein ID WP_258582843.1
Coordinates 5626581..5626808 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DBIPINDM_RS31385 (DBIPINDM_005306) 5621986..5623020 + 1035 WP_258582840.1 ABC transporter permease -
DBIPINDM_RS31390 (DBIPINDM_005307) 5623033..5624190 + 1158 WP_258582841.1 ABC transporter permease -
DBIPINDM_RS31395 (DBIPINDM_005308) 5624239..5626425 + 2187 WP_258582842.1 ABC transporter ATP-binding protein -
DBIPINDM_RS31400 (DBIPINDM_005309) 5626581..5626808 + 228 WP_258582843.1 CopG family transcriptional regulator Antitoxin
DBIPINDM_RS31405 (DBIPINDM_005310) 5626805..5627242 + 438 WP_258582844.1 PIN domain-containing protein Toxin
DBIPINDM_RS31410 (DBIPINDM_005311) 5627324..5627914 - 591 WP_258582845.1 transglycosylase SLT domain-containing protein -
DBIPINDM_RS31415 (DBIPINDM_005312) 5628132..5629670 + 1539 WP_258582846.1 trimethylamine methyltransferase family protein -
DBIPINDM_RS31420 (DBIPINDM_005313) 5629728..5632154 + 2427 WP_258582847.1 FAD-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-131)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15436.63 Da        Isoelectric Point: 7.1281

>T212016 WP_258582844.1 NZ_CP080531:5626805-5627242 [Mesorhizobium sp. AR02]
VTFLLDVNVLIALIDPAHVAHEDGHRWFQSTGHSSWATCPITENGVIRILSNPKYPNSPGSPAVVAQIVGKLHALSGHQF
WPDDISLVGSSDIDAAKILTPAQVTDSYLLGLAKARGGQLATFDRKLSTAAVKGGKPILHLIQSE

Download         Length: 438 bp

>T212016 NZ_CP106909:6993-7343 [Klebsiella pneumoniae]
ATGTGGGTCATCGAGACAACCGACACCTTTGATGAGTGGTTCGATGCTCTGGATGATACCGATAGAGCAAACGTGCTGGC
TTCGATGATGGTGCTGCGAGATAGAGGCCCCATGCTGTCGAGGCCATACGCGGATACTGTTAACGGTTCATCCTACAGCA
ACATGAAAGAGCTTCGGGTCCAAAGCAAAGGAGATCCTATCAGAGCGTTCTTTGCGTTCGATCCAAAGCGTAAGGGGATT
CTTCTCTGCGCCGGTAACAAGACCGGGGACGAGAAAAGGTTTTATGAAGTAATGATCCCAATTGCAGACCGTGAGTTTGC
GGCGCACTTGGATAAATTGAAGAAGGAGTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8221.38 Da        Isoelectric Point: 5.7974

>AT212016 WP_258582843.1 NZ_CP080531:5626581-5626808 [Mesorhizobium sp. AR02]
VRTTLAIDDDVLLAAKAMARQQDRSIGEVISDLARHSLRRPRAGSERNGIPLLASRSDGPMVDLEMVNALRDELP

Download         Length: 228 bp

>AT212016 NZ_CP106909:7348-7650 [Klebsiella pneumoniae]
ATGGCAAGAACTCTTGACCAAATGCTGGCAACAGAAAAGCCTGAGGTTGTTGCCAAAGCACAGAAAGCGGCCACTGAGAT
GTTACTGAACATCCACTTGGCAGAGCTTCGTGATCGCATGAACCTTACCCAGGGGGAAATTGCTGCATCTCTGGGTGTGA
GACAGCCGACAGTCTCCGAGATGGAAAAACCTGGACGAGATCTCAAGCTGTCGTCCATTAAGCGGTACGTTGAGGCCTCC
GGTGGCAAGCTACGCCTCGATGTTGAACTTCCGGACGGCACCCACTACGGCTTTGCCGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References