Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 404368..404966 Replicon plasmid pMspAR07d
Accession NZ_CP080528
Organism Mesorhizobium sp. AR07

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BPNPMPFG_RS38075 Protein ID WP_183455094.1
Coordinates 404673..404966 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BPNPMPFG_RS38070 Protein ID WP_183455093.1
Coordinates 404368..404676 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BPNPMPFG_RS38050 (BPNPMPFG_006858) 400613..401500 + 888 WP_258598940.1 hypothetical protein -
BPNPMPFG_RS38055 401497..401818 + 322 Protein_384 hypothetical protein -
BPNPMPFG_RS38060 (BPNPMPFG_006860) 402302..402889 + 588 WP_258598941.1 hypothetical protein -
BPNPMPFG_RS38065 (BPNPMPFG_006861) 403224..404150 + 927 WP_258598943.1 ArdC family protein -
BPNPMPFG_RS38070 (BPNPMPFG_006862) 404368..404676 + 309 WP_183455093.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
BPNPMPFG_RS38075 (BPNPMPFG_006863) 404673..404966 + 294 WP_183455094.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BPNPMPFG_RS38080 (BPNPMPFG_006864) 405608..405919 + 312 WP_183455095.1 DUF736 domain-containing protein -
BPNPMPFG_RS38085 (BPNPMPFG_006865) 406035..406280 + 246 WP_183455096.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
BPNPMPFG_RS38090 (BPNPMPFG_006866) 406277..406663 + 387 WP_183465714.1 type II toxin-antitoxin system VapC family toxin -
BPNPMPFG_RS38095 (BPNPMPFG_006867) 407365..407676 + 312 WP_183455095.1 DUF736 domain-containing protein -
BPNPMPFG_RS38100 (BPNPMPFG_006868) 407738..407914 + 177 WP_183465713.1 hypothetical protein -
BPNPMPFG_RS38105 (BPNPMPFG_006869) 407935..408162 + 228 WP_183455098.1 CopG family transcriptional regulator -
BPNPMPFG_RS38110 (BPNPMPFG_006870) 408159..408596 + 438 WP_183455099.1 PIN domain-containing protein -
BPNPMPFG_RS38115 (BPNPMPFG_006871) 408634..408912 - 279 WP_183455100.1 HU family DNA-binding protein -
BPNPMPFG_RS38120 (BPNPMPFG_006872) 409032..409277 - 246 WP_183465712.1 WGR domain-containing protein -
BPNPMPFG_RS38125 (BPNPMPFG_006873) 409652..409835 - 184 Protein_398 type IV secretory system conjugative DNA transfer family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - kdsA / gmd 1..1021442 1021442


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-57)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10896.41 Da        Isoelectric Point: 6.0723

>T212003 WP_183455094.1 NZ_CP080528:404673-404966 [Mesorhizobium sp. AR07]
MRLKWSAFALADRDDIFTHIEAESPRAAAAVDEHIAQAVLRLVEFPESGRPGRVPGTRELVISRTPYIAAYVLTHDAIRI
LRVLHGAQMWPEDFSSD

Download         Length: 294 bp

>T212003 NZ_CP106906:878258-878665 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCGTGC
GCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCCGAA
TGGGAAATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGGACA
GCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGGCGC
AGGAGTAA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11096.48 Da        Isoelectric Point: 5.6994

>AT212003 WP_183455093.1 NZ_CP080528:404368-404676 [Mesorhizobium sp. AR07]
MATNALVQTRIDSNIRDRAASVLEGMGLTVSDVVRILLTRTANEGALPLELISNSEAHDAWFRAKVMQALEDTRTDVTAE
DVETHFASRRAAALRKAGTTQS

Download         Length: 309 bp

>AT212003 NZ_CP106906:878011-878277 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References