Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafQ-relB/YafQ-RelB
Location 6226996..6227527 Replicon chromosome
Accession NZ_CP080525
Organism Mesorhizobium sp. AR07

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag BPNPMPFG_RS30690 Protein ID WP_258592295.1
Coordinates 6226996..6227268 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BPNPMPFG_RS30695 Protein ID WP_258592296.1
Coordinates 6227270..6227527 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BPNPMPFG_RS30670 (BPNPMPFG_006083) 6222315..6223826 + 1512 WP_258592292.1 sugar ABC transporter ATP-binding protein -
BPNPMPFG_RS30675 (BPNPMPFG_006084) 6223909..6224904 + 996 WP_258592293.1 ABC transporter permease -
BPNPMPFG_RS30680 (BPNPMPFG_006085) 6224954..6226006 + 1053 WP_258592294.1 substrate-binding domain-containing protein -
BPNPMPFG_RS30685 (BPNPMPFG_006086) 6226109..6226954 + 846 WP_258596996.1 acyl-CoA thioester hydrolase/BAAT C-terminal domain-containing protein -
BPNPMPFG_RS30690 (BPNPMPFG_006087) 6226996..6227268 - 273 WP_258592295.1 type II toxin-antitoxin system YafQ family toxin Toxin
BPNPMPFG_RS30695 (BPNPMPFG_006088) 6227270..6227527 - 258 WP_258592296.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
BPNPMPFG_RS30700 (BPNPMPFG_006089) 6227643..6229697 - 2055 WP_258592297.1 bifunctional aldolase/short-chain dehydrogenase -
BPNPMPFG_RS30705 (BPNPMPFG_006090) 6229790..6230749 - 960 WP_258592298.1 sugar-binding transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(7-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(6-82)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10380.81 Da        Isoelectric Point: 7.3178

>T212000 WP_258592295.1 NZ_CP080525:c6227268-6226996 [Mesorhizobium sp. AR07]
VLTPVRSGQFRRDVKRAEKRGKDLGKLRELLGLLIAEDELPASYKDHPLKGDWKGYRDAHIEPDWLLIYRVAPDELQLAR
TGSHSDLFNE

Download         Length: 273 bp

>T212000 NZ_CP106906:329307-329675 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCAGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACTCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCGGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCGGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGCTTGCGCGGATGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9195.62 Da        Isoelectric Point: 6.3276

>AT212000 WP_258592296.1 NZ_CP080525:c6227527-6227270 [Mesorhizobium sp. AR07]
MATDTVVRARIDTATKDQATEALAAMGLSISDAIRLLLVRVAADKEFPFQVKVPNATTRKAMAELEEGKGKRFASADELF
KDLGL

Download         Length: 258 bp

>AT212000 NZ_CP106906:329089-329310 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGACGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References