Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 3971401..3972062 Replicon chromosome
Accession NZ_CP080525
Organism Mesorhizobium sp. AR07

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BPNPMPFG_RS20280 Protein ID WP_258590458.1
Coordinates 3971625..3972062 (+) Length 146 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BPNPMPFG_RS20275 Protein ID WP_258590457.1
Coordinates 3971401..3971628 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BPNPMPFG_RS20245 (BPNPMPFG_004010) 3966512..3966781 - 270 WP_027031700.1 50S ribosomal protein L27 -
BPNPMPFG_RS20250 (BPNPMPFG_004011) 3966879..3967541 - 663 WP_258590453.1 50S ribosomal protein L21 -
BPNPMPFG_RS20260 (BPNPMPFG_004013) 3968345..3968554 + 210 WP_258590454.1 lipoprotein -
BPNPMPFG_RS20265 (BPNPMPFG_004014) 3968784..3969848 - 1065 WP_258590455.1 hypothetical protein -
BPNPMPFG_RS20270 (BPNPMPFG_004015) 3970084..3971058 - 975 WP_258590456.1 Tim44 domain-containing protein -
BPNPMPFG_RS20275 (BPNPMPFG_004016) 3971401..3971628 + 228 WP_258590457.1 CopG family transcriptional regulator Antitoxin
BPNPMPFG_RS20280 (BPNPMPFG_004017) 3971625..3972062 + 438 WP_258590458.1 PIN domain-containing protein Toxin
BPNPMPFG_RS20285 3972449..3973408 + 960 WP_258590459.1 DUF1186 domain-containing protein -
BPNPMPFG_RS20290 (BPNPMPFG_004019) 3973443..3975285 - 1843 Protein_4005 DNA helicase RecQ -
BPNPMPFG_RS20295 (BPNPMPFG_004020) 3975565..3976986 + 1422 WP_258590460.1 coniferyl aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-131)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15375.49 Da        Isoelectric Point: 6.2086

>T211997 WP_258590458.1 NZ_CP080525:3971625-3972062 [Mesorhizobium sp. AR07]
VTFLLDINVVIALIDPGHVAHDDAHRWFEALGSVSWATCPITENGVIRIVGNPKYPNNPGSPAIVAEIVGKLRALPGHSF
WSDDVSLVGSDDIDATKILTSAQVTDTYLLALAKTHGGQLATFDRKLSVAAVKNGKADLHLISGN

Download         Length: 438 bp

>T211997 NZ_CP106896:c52139-51723 [Enterobacter hormaechei]
ATGAAGAAAACCTGGATGCTCGACACTAACATCTGCTCGTTCATCATGCGCGAGCAGCCGGCAGCGGTGCTGAAGCGCCT
GGAGCAGGCGGTGCTGCGCGGTGATCGCATCGTGGTCTCGGCCGTGACGTACGCCGAGATGCGCTTCGGCGCCACCGGCC
CGAAGGCCTCGCCGCGCCATATTCAGCTGGTCGACGCGTTCTGCGCGCGCCTCGATGCTGTCCTGCCCTGGGACCGCGCC
GCGGTGGACGCCACGACGGACATCCGGGTGGCGCTGCGCCTCGCCGGGACGCCGATCGGCCCGAACGACACGGCCATTGC
CGGGCACGCCATCGCGGCCAGTGCCGTCCTGGTGACGAACAATGTGAGAGAGTTTGCGCGGGTCCCGGGCCTGATGCTGG
AAGACTGGGTAAAATAA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8385.57 Da        Isoelectric Point: 6.2913

>AT211997 WP_258590457.1 NZ_CP080525:3971401-3971628 [Mesorhizobium sp. AR07]
MRTTLAIDDDVLLAAKAMARQQERSLGEVISDLARRSLRRPFSGNERNGIPLLSPRQDTPSVTLEIVNTLRDELP

Download         Length: 228 bp

>AT211997 NZ_CP106896:c52366-52136 [Enterobacter hormaechei]
ATGCGCACAGTTTCTATATTTAAAAACGGCAATAACCGCGCCATCCGTCTGCCCCGGGACCTGGATTTTGACGGCGTCAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATCATTCTGCGTCCCGTCCGGCCGACCTGGGGCTCATTCGCGCAGCTGG
ACAGGGCCGATCCGGACTTTATGGCGGAGCGTGAGGATGTGGTCAGCGATGAAGGACGCTTTGAGCCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References