Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 2505601..2506217 Replicon chromosome
Accession NZ_CP080525
Organism Mesorhizobium sp. AR07

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BPNPMPFG_RS12895 Protein ID WP_258595754.1
Coordinates 2505828..2506217 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BPNPMPFG_RS12890 Protein ID WP_258595753.1
Coordinates 2505601..2505831 (+) Length 77 a.a.

Genomic Context

BPNPMPFG_RS12870BPNPMPFG_RS12875BPNPMPFG_RS12880BPNPMPFG_RS12890BPNPMPFG_RS12895BPNPMPFG_RS12910BPNPMPFG_RS12925BPNPMPFG_RS12885BPNPMPFG_RS12900BPNPMPFG_RS12905BPNPMPFG_RS12915BPNPMPFG_RS12920
Location: 2501141..2503348 (2208 bp)
Type: Others
Protein ID: WP_258595749.1
Location: 2503743..2504177 (435 bp)
Type: Others
Protein ID: WP_258595750.1
Location: 2504248..2504484 (237 bp)
Type: Others
Protein ID: WP_258595751.1
Location: 2505601..2505831 (231 bp)
Type: Antitoxin
Protein ID: WP_258595753.1
Location: 2505828..2506217 (390 bp)
Type: Toxin
Protein ID: WP_258595754.1
Location: 2508017..2508964 (948 bp)
Type: Others
Protein ID: WP_258595759.1
Location: 2509982..2510608 (627 bp)
Type: Others
Protein ID: WP_258595762.1
Location: 2504520..2505386 (867 bp)
Type: Others
Protein ID: WP_258595752.1
Location: 2506218..2506910 (693 bp)
Type: Others
Protein ID: WP_258595756.1
Location: 2506919..2507791 (873 bp)
Type: Others
Protein ID: WP_258595758.1
Location: 2509102..2509323 (222 bp)
Type: Others
Protein ID: WP_258595760.1
Location: 2509490..2509915 (426 bp)
Type: Others
Protein ID: WP_258595761.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BPNPMPFG_RS12870 (BPNPMPFG_002550)2501141..2503348+2208WP_258595749.1OmpA family protein-
BPNPMPFG_RS12875 (BPNPMPFG_002551)2503743..2504177+435WP_258595750.1YqhA family protein-
BPNPMPFG_RS12880 (BPNPMPFG_002552)2504248..2504484+237WP_258595751.1type II toxin-antitoxin system ParD family antitoxin-
BPNPMPFG_RS12885 (BPNPMPFG_002553)2504520..2505386-867WP_258595752.1NAD(P)-dependent oxidoreductase-
BPNPMPFG_RS12890 (BPNPMPFG_002554)2505601..2505831+231WP_258595753.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
BPNPMPFG_RS12895 (BPNPMPFG_002555)2505828..2506217+390WP_258595754.1type II toxin-antitoxin system VapC family toxinToxin
BPNPMPFG_RS12900 (BPNPMPFG_002556)2506218..2506910-693WP_258595756.1helix-turn-helix transcriptional regulator-
BPNPMPFG_RS12905 (BPNPMPFG_002557)2506919..2507791-873WP_258595758.1S1C family serine protease-
BPNPMPFG_RS12910 (BPNPMPFG_002558)2508017..2508964+948WP_258595759.1trypsin-like peptidase domain-containing protein-
BPNPMPFG_RS12915 (BPNPMPFG_002559)2509102..2509323-222WP_258595760.1hypothetical protein-
BPNPMPFG_RS12920 (BPNPMPFG_002560)2509490..2509915-426WP_258595761.1VOC family protein-
BPNPMPFG_RS12925 (BPNPMPFG_002561)2509982..2510608+627WP_258595762.1TetR/AcrR family transcriptional regulator-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-123)

Antitoxin

Antitoxin VapB-like

(1-74)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14200.46 Da        Isoelectric Point: 6.4650

>T211996 WP_258595754.1 NZ_CP080525:2505828-2506217 [Mesorhizobium sp. AR07]
MIIDSSVLVAILRIEPGYERFVLAIAQAKRRLLAAPTFLETTMVLAGGRQDDILDRLDSFLRSSSIETIAFTADHAAVAR
QAFLRYGKGRHPAALNFGDCIAYATARLEAMPLLFKGDDFRLTDIEAAI

Download         Length: 390 bp

>T211996 NZ_CP106896:32513-32998 [Enterobacter hormaechei]
GTGGGACATGTAACAGCACCAGAACCTCTGTCCGCTTTTCATCAGGTGGCTGAGTTCGTGAGCGGTGAAACTGTGCTCGA
TGACTGGTTAAAGCAGAAAGGCCTAAAAAACCAGGCTCTCGGAGCGGCCAGAACGTTTGTGGTATGTAAGAAAGATACGA
AGCAAATAGCCGGCTTTTACTCTCTGGCCACCGGGAGCGTCAATCATACTGAAGCGACAGGGAATCTTCGGCGTAACATG
CCAGATCCCATCCCTGTCATTATACTTGCCCGCCTTGCTGTCGATCTCTCATTGCGCGGAAAAGGGCTTGGCGCTGATTT
ACTTCATGATGCAGTGCTTCGTTGCTATCGGGTTGCCGAGAATATTGGTGTACGTGCAATCATGGTTCATGCGCTCACAG
AAGAAGCCAAAAATTTCTACATTCACCATGGTTTCAAACCATCACAAACTCAGCCGCGGACATTGTTCCTCAGACTTCCT
CAATAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8789.97 Da        Isoelectric Point: 5.2072

>AT211996 WP_258595753.1 NZ_CP080525:2505601-2505831 [Mesorhizobium sp. AR07]
MARELARRRRVSVTEAIRQSLEREVARERLVPRDETDDLFQRLMAIADSAGKVPKRENAMTDDEILGYDEFGIPTK

Download         Length: 231 bp

>AT211996 NZ_CP106896:32259-32525 [Enterobacter hormaechei]
ATGAAATCAGATGTTCAACTTAACCTTAGAGCTAAGGAATCGCAGCGGGCGCTCATAGATGCGGCTGCGGAAATCCTCCA
CAAGTCACGTACAGATTTCATTCTTGAAATGGCCTGTCAGGCTGCCGAGAATGTGATACTCGATCGCCGGGTATTTAACT
TTAACGATGAGCAATATGCGGAGTTCATCGATATGCTTGATGCACCGGTCGCAGATGATCCCATTATCGAAAAACTGCTG
GCAAGGAAACCTCAGTGGGACATGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References