Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 1782941..1783707 Replicon chromosome
Accession NZ_CP080525
Organism Mesorhizobium sp. AR07

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag BPNPMPFG_RS09030 Protein ID WP_258596679.1
Coordinates 1782941..1783426 (-) Length 162 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag BPNPMPFG_RS09035 Protein ID WP_258594812.1
Coordinates 1783426..1783707 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BPNPMPFG_RS09010 (BPNPMPFG_001793) 1779069..1780097 + 1029 WP_258594806.1 sulfate ABC transporter substrate-binding protein -
BPNPMPFG_RS09015 (BPNPMPFG_001794) 1780114..1780965 + 852 WP_258594808.1 sulfate ABC transporter permease subunit CysT -
BPNPMPFG_RS09020 (BPNPMPFG_001795) 1780958..1781842 + 885 WP_258594809.1 sulfate ABC transporter permease subunit CysW -
BPNPMPFG_RS09025 (BPNPMPFG_001796) 1781855..1782901 + 1047 WP_258594810.1 sulfate/molybdate ABC transporter ATP-binding protein -
BPNPMPFG_RS09030 (BPNPMPFG_001797) 1782941..1783426 - 486 WP_258596679.1 GNAT family N-acetyltransferase Toxin
BPNPMPFG_RS09035 (BPNPMPFG_001798) 1783426..1783707 - 282 WP_258594812.1 DUF1778 domain-containing protein Antitoxin
BPNPMPFG_RS09040 (BPNPMPFG_001799) 1783968..1784954 + 987 WP_258594813.1 sulfate ABC transporter substrate-binding protein -
BPNPMPFG_RS09045 (BPNPMPFG_001800) 1785332..1785781 + 450 WP_006202816.1 Rrf2 family transcriptional regulator -
BPNPMPFG_RS09050 (BPNPMPFG_001801) 1785823..1786371 - 549 WP_258594820.1 gluconokinase -
BPNPMPFG_RS09055 (BPNPMPFG_001802) 1786374..1787360 - 987 WP_258594822.1 ABC transporter permease -
BPNPMPFG_RS09060 (BPNPMPFG_001803) 1787357..1788337 - 981 WP_258594823.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-142)

Antitoxin

Vibrio phage ICP1, Orf50

(3-78)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 16976.55 Da        Isoelectric Point: 8.9322

>T211995 WP_258596679.1 NZ_CP080525:c1783426-1782941 [Mesorhizobium sp. AR07]
MLSAPTPLAENHDVEFFQSGTESLDQWLHLRARANQVSGASRTYVVAEGARVVGYYCLSSGGLDLAEAPGAIRRNMPDPI
PMVVLGRLAVDAGWQGKGLGAALLQDAVLRAGHAATILGIRGIFVHAISDEAKAFHVRYGFAASPKNPMTLVLSLKGALK
G

Download         Length: 486 bp

>T211995 NZ_CP106895:c210937-210650 [Enterobacter hormaechei]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10636.23 Da        Isoelectric Point: 9.5604

>AT211995 WP_258594812.1 NZ_CP080525:c1783707-1783426 [Mesorhizobium sp. AR07]
MTKTRPETHAKPVNLRIREDVRMLIDRAAKIRGKTRSDFMIDAAYRAAEDTLLDQALIKVDPESYRHYLDILDGPPSGEG
FARLMNVPKPWQG

Download         Length: 282 bp

>AT211995 NZ_CP106895:c211176-210937 [Enterobacter hormaechei]
ATGGGTAGCATTAACCTACGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGCGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGACTTCGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References