Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 721973..722568 Replicon chromosome
Accession NZ_CP080525
Organism Mesorhizobium sp. AR07

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag BPNPMPFG_RS03805 Protein ID WP_258593295.1
Coordinates 722278..722568 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BPNPMPFG_RS03800 Protein ID WP_258593294.1
Coordinates 721973..722281 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BPNPMPFG_RS03785 (BPNPMPFG_000753) 718026..718364 - 339 WP_006205430.1 P-II family nitrogen regulator -
BPNPMPFG_RS03790 (BPNPMPFG_000754) 718722..720269 + 1548 WP_258593292.1 NAD(P)H-hydrate dehydratase -
BPNPMPFG_RS03795 (BPNPMPFG_000755) 720272..721804 - 1533 WP_258593293.1 acyl-CoA carboxylase subunit beta -
BPNPMPFG_RS03800 (BPNPMPFG_000756) 721973..722281 - 309 WP_258593294.1 putative addiction module antidote protein Antitoxin
BPNPMPFG_RS03805 (BPNPMPFG_000757) 722278..722568 - 291 WP_258593295.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BPNPMPFG_RS03810 (BPNPMPFG_000758) 723117..724538 + 1422 WP_258593296.1 DEAD/DEAH box helicase -
BPNPMPFG_RS03815 (BPNPMPFG_000759) 724647..725621 - 975 WP_258593297.1 alpha/beta hydrolase -
BPNPMPFG_RS03820 (BPNPMPFG_000760) 725717..726538 - 822 WP_258593298.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-95)

Antitoxin

Uncharacterized protein HI1420

(5-91)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10866.72 Da        Isoelectric Point: 10.1848

>T211994 WP_258593295.1 NZ_CP080525:c722568-722278 [Mesorhizobium sp. AR07]
VIEVRKTVEFSEWFKSLKDIRAKARIQVRIDRVELGNLGDTKFFDGIGELRIDYGPGYRVYFVKAGNTIIILLCGGDKSS
QKADIKKAITMAKEVK

Download         Length: 291 bp

>T211994 NZ_CP106895:93348-94673 [Enterobacter hormaechei]
ATGAGCCGGAAACAGCAGCGTCTGGCAATCTGGATGAACGGAATCAAAGTCGGATACTGGGAAAAAAGTAAAGGGGTAGA
CAGCTTACAATACCTTCCTGACTGGAGTGCAGACGAACAGGGAAGGCCGCTGTCATTGTCCCTTCCTTTTACTCCCGGGA
ACCAGGTCTGGCGTGGAAATGTGGTACGTGACTATTTTGATAATTTACTCCCGGACAGCGAAGGCATACGCAGACGTCTG
GCAATGCGTTACAAGGCCGATAGCCTGGAGCCTTTTGATCTTCTGACGGAGCTGGGAAAAGACTGCGTGGGCGCGATACA
GCTGCTTCATGACGGAGATGAACCCACAGATTTATATTCCGTGAAGTATCACCCGCTTACTGAATCAGAAATTGCGGCAA
CTTTGCGTAATACCACGGAGACATTGCTACCGGGCAGGCCAGAAGATAACGACGACTTACGTTTATCTATTGCCGGTGCT
CAGGAGAAAACAGCCCTACTGTGGCATGAAGATCGGTGGTGTATGCCGGAGGGTAATACACCAACGACGCATATATTCAA
GCTACCGCTCGGACTTGTGGGGAACATGAAAGCCGACATGCGCTCGTCGGTTGAAAATGAATGGCTCTGCTCGGTACTTC
TCGAACAGTACGGGCTCCCCGTGGCAAGAACGCAGATTGCTCACTTTGAAGATCAGAAAGCGCTGGTGGTAGAACGTTTT
GACCGAAAATGGTCAGGAAACGGACAATGGATCATTCGTTTACCCCAGGAGGATATGTGTCAGGCCCTGGGCATTTCGCC
ATTACGAAAATATCAGGCGGACGGCGGGCCAGGTATATCGGAAATTATGGAAGTTCTGAGTAATTCAGACCGTGCTGAGC
GTGACAAAGCGCAGTTTTTTATGACGCAGATAGTTTTCTGGATGATGGCCGCAACAGATGGCCACGCTAAAAATTTCAGT
ATTTCTATTGGGCCACAGGGACGTTATCACCTTACACCACTCTATGATGTGTTGTCGGCATGGCCGGTGATCGGTCATGG
GAACAATCAGATATCCTGGCAGAAGTGCAAACTGGCGATGGCCGTACGTGGCAGTAGCAACTATTACCAGATATATCGAA
TACAACGACGCCACTGGATCAGGCATGGTGAGATAACCGGCCTGAGTAAACAGCAGACAGAGGCGATGATAGAGGAAATC
ATCGCCAGAACCCCGGGTGTCATTGAACGTGTTAGCGGGCTTCTTCCGGACCAGTTCCCCCAGCAGCTTGCGGAAAGTAT
TTTTGATGGAATGAGGCAGCAATGCAGGCGCCTGGCTGAGAAATGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 10676.15 Da        Isoelectric Point: 4.3885

>AT211994 WP_258593294.1 NZ_CP080525:c722281-721973 [Mesorhizobium sp. AR07]
VTIETTKWDASEFLDGEEAIFAYIEAAFEDGDPAIITHALGNVARARGMTSIAKDAGVTREALYKALSEKGDPKLSTLLG
VMKALGLRLTAEAVPAEPGIAG

Download         Length: 309 bp

>AT211994 NZ_CP106895:93050-93343 [Enterobacter hormaechei]
ATCAATAATGATTACCCGTTAAACACGCTCAACCAGTTGCGTCCCTTGCTCATTGGTTTTCGCAAGGCGAATGGCCTGAC
GCAAAAAGACCTGTCCGAAAGGTTAGGGGTCACTCAACAGACATACTCACGTCTGGAAGCCAACCCTGCCAGTGCGAGCA
TTGAACGGCTATTCAAGGTGTTTTCTATCCTGGGCGTAAAAATCAGCTTCTCCTCGACAACCGCCTCTTCAGAGGGGAAG
CAGACGGAAGAAATGCTTAAATCAAACTCACCTGCACGACAGGAGAAATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References