Detailed information of TA system TA211992

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-Xre
• Location: 5573664..5574534
• Replicon: chromosome
• Accession: NZ_CP080524
• Organism: Mesorhizobium sp. AR10

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: LHFGNBLO_RS30800
• Protein ID: WP_258603632.1
• Coordinates: 5573664..5574170 (-)
• Length: 169 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: LHFGNBLO_RS30805
• Protein ID: WP_258603634.1
• Coordinates: 5574163..5574534 (-)
• Length: 124 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LHFGNBLO_RS30780 (LHFGNBLO_005416)	5569801..5570703	-	903	WP_258603622.1	cytochrome c oxidase subunit II	-
LHFGNBLO_RS30785 (LHFGNBLO_005417)	5571076..5571624	+	549	WP_258603624.1	invasion associated locus B family protein	-
LHFGNBLO_RS30790 (LHFGNBLO_005418)	5571635..5572126	+	492	WP_258603629.1	GNAT family N-acetyltransferase	-
LHFGNBLO_RS30795 (LHFGNBLO_005419)	5572211..5573623	+	1413	WP_258603630.1	metalloprotease TldD	-
LHFGNBLO_RS30800 (LHFGNBLO_005420)	5573664..5574170	-	507	WP_258603632.1	RES domain-containing protein	Toxin
LHFGNBLO_RS30805 (LHFGNBLO_005421)	5574163..5574534	-	372	WP_258603634.1	MbcA/ParS/Xre antitoxin family protein	Antitoxin
LHFGNBLO_RS30810 (LHFGNBLO_005422)	5574632..5575873	-	1242	WP_258603636.1	class I SAM-dependent RNA methyltransferase	-
LHFGNBLO_RS30815 (LHFGNBLO_005423)	5575870..5576679	-	810	WP_258603641.1	TlyA family RNA methyltransferase	-
LHFGNBLO_RS30820 (LHFGNBLO_005424)	5576765..5577058	-	294	WP_258603644.1	hypothetical protein	-
LHFGNBLO_RS30825 (LHFGNBLO_005425)	5577207..5579120	-	1914	WP_258603646.1	1-deoxy-D-xylulose-5-phosphate synthase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (7-161)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (71-120)

Sequences

Toxin

Protein

• Length: 169 a.a.
• Molecular weight: 18871.44 Da
• Isoelectric Point: 6.2204

>T211992 WP_258603632.1 NZ_CP080524:c5574170-5573664 [Mesorhizobium sp. AR10]
MPETRLTLWRAFVPRWAHLPLSGEGAVRFGGRWNPVGAPAVYAARELSTAWAEYNQGFVQHPALIAQLELSGARLADLTE
PDTLTKLDTTADIHRCEWRDIMDRGLVPETHTLRDRLLANGLHGVIYPSFMSPGGTCVALWRWNEDDAPRLDVVDPDHRL
PKTPASWL

Nucleotide

• Length: 507 bp

>T211992 NZ_CP106894:c2811222-2811119 [Enterobacter hormaechei]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin

Protein

• Length: 124 a.a.
• Molecular weight: 13223.32 Da
• Isoelectric Point: 9.9467

>AT211992 WP_258603634.1 NZ_CP080524:c5574534-5574163 [Mesorhizobium sp. AR10]
MNTAILEIPASRFGEERTPFLSARRVAELLGVNLTELAGLTGVARNTLAAKTGARKVDAALSPIVRILAMAGEMAGDEQR
AAIWFKHQPIPGWAGKTAYDLVREGKTDKVLAYLEAVRSGIYA

Nucleotide

• Length: 372 bp

>AT211992 NZ_CP106894:2811112-2811315 [Enterobacter hormaechei]
AATAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGTAAAAGTG
GTCTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC