Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-Xre
Location 5573664..5574534 Replicon chromosome
Accession NZ_CP080524
Organism Mesorhizobium sp. AR10

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LHFGNBLO_RS30800 Protein ID WP_258603632.1
Coordinates 5573664..5574170 (-) Length 169 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LHFGNBLO_RS30805 Protein ID WP_258603634.1
Coordinates 5574163..5574534 (-) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LHFGNBLO_RS30780 (LHFGNBLO_005416) 5569801..5570703 - 903 WP_258603622.1 cytochrome c oxidase subunit II -
LHFGNBLO_RS30785 (LHFGNBLO_005417) 5571076..5571624 + 549 WP_258603624.1 invasion associated locus B family protein -
LHFGNBLO_RS30790 (LHFGNBLO_005418) 5571635..5572126 + 492 WP_258603629.1 GNAT family N-acetyltransferase -
LHFGNBLO_RS30795 (LHFGNBLO_005419) 5572211..5573623 + 1413 WP_258603630.1 metalloprotease TldD -
LHFGNBLO_RS30800 (LHFGNBLO_005420) 5573664..5574170 - 507 WP_258603632.1 RES domain-containing protein Toxin
LHFGNBLO_RS30805 (LHFGNBLO_005421) 5574163..5574534 - 372 WP_258603634.1 MbcA/ParS/Xre antitoxin family protein Antitoxin
LHFGNBLO_RS30810 (LHFGNBLO_005422) 5574632..5575873 - 1242 WP_258603636.1 class I SAM-dependent RNA methyltransferase -
LHFGNBLO_RS30815 (LHFGNBLO_005423) 5575870..5576679 - 810 WP_258603641.1 TlyA family RNA methyltransferase -
LHFGNBLO_RS30820 (LHFGNBLO_005424) 5576765..5577058 - 294 WP_258603644.1 hypothetical protein -
LHFGNBLO_RS30825 (LHFGNBLO_005425) 5577207..5579120 - 1914 WP_258603646.1 1-deoxy-D-xylulose-5-phosphate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(7-161)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(71-120)


Sequences

Toxin        


Download         Length: 169 a.a.        Molecular weight: 18871.44 Da        Isoelectric Point: 6.2204

>T211992 WP_258603632.1 NZ_CP080524:c5574170-5573664 [Mesorhizobium sp. AR10]
MPETRLTLWRAFVPRWAHLPLSGEGAVRFGGRWNPVGAPAVYAARELSTAWAEYNQGFVQHPALIAQLELSGARLADLTE
PDTLTKLDTTADIHRCEWRDIMDRGLVPETHTLRDRLLANGLHGVIYPSFMSPGGTCVALWRWNEDDAPRLDVVDPDHRL
PKTPASWL

Download         Length: 507 bp

>T211992 NZ_CP106894:c2811222-2811119 [Enterobacter hormaechei]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13223.32 Da        Isoelectric Point: 9.9467

>AT211992 WP_258603634.1 NZ_CP080524:c5574534-5574163 [Mesorhizobium sp. AR10]
MNTAILEIPASRFGEERTPFLSARRVAELLGVNLTELAGLTGVARNTLAAKTGARKVDAALSPIVRILAMAGEMAGDEQR
AAIWFKHQPIPGWAGKTAYDLVREGKTDKVLAYLEAVRSGIYA

Download         Length: 372 bp

>AT211992 NZ_CP106894:2811112-2811315 [Enterobacter hormaechei]
AATAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGTAAAAGTG
GTCTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References