Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE-HTH
Location 5263636..5264107 Replicon chromosome
Accession NZ_CP080524
Organism Mesorhizobium sp. AR10

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LHFGNBLO_RS29330 Protein ID WP_258602833.1
Coordinates 5263636..5263902 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag LHFGNBLO_RS29335 Protein ID WP_258602840.1
Coordinates 5263886..5264107 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LHFGNBLO_RS29305 (LHFGNBLO_005122) 5258739..5259629 - 891 WP_258602812.1 YicC/YloC family endoribonuclease -
LHFGNBLO_RS29310 (LHFGNBLO_005123) 5259814..5261046 - 1233 WP_258602813.1 endolytic transglycosylase MltG -
LHFGNBLO_RS29315 (LHFGNBLO_005124) 5261134..5262396 - 1263 WP_258602821.1 beta-ketoacyl-ACP synthase II -
LHFGNBLO_RS29320 (LHFGNBLO_005125) 5262431..5262667 - 237 WP_056109445.1 acyl carrier protein -
LHFGNBLO_RS29325 (LHFGNBLO_005126) 5262857..5263594 - 738 WP_258602830.1 3-oxoacyl-[acyl-carrier-protein] reductase -
LHFGNBLO_RS29330 (LHFGNBLO_005127) 5263636..5263902 - 267 WP_258602833.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LHFGNBLO_RS29335 (LHFGNBLO_005128) 5263886..5264107 - 222 WP_258602840.1 ribbon-helix-helix protein, CopG family Antitoxin
LHFGNBLO_RS29340 (LHFGNBLO_005129) 5264194..5265141 - 948 WP_258602842.1 ACP S-malonyltransferase -
LHFGNBLO_RS29345 (LHFGNBLO_005130) 5265403..5267325 + 1923 WP_258602844.1 LTA synthase family protein -
LHFGNBLO_RS29350 (LHFGNBLO_005131) 5267634..5268134 + 501 WP_258602846.1 30S ribosomal protein S6 -
LHFGNBLO_RS29355 (LHFGNBLO_005132) 5268134..5268382 + 249 WP_006203718.1 30S ribosomal protein S18 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-87)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-39)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10437.07 Da        Isoelectric Point: 10.1808

>T211990 WP_258602833.1 NZ_CP080524:c5263902-5263636 [Mesorhizobium sp. AR10]
VAWTLEYARSARKFVEKLDPQTRHRIRDFIENRIAVLDNPRELGKPLKGPLATFWRYRVGDYRIICDVQDDRLVILVVTI
GHRGDVYR

Download         Length: 267 bp

>T211990 NZ_CP106894:c1116241-1116023 [Enterobacter hormaechei]
ATGTCTGATAAACCATTAACAAAAGTCGATTATTTGATGCGCCTGCGACGCTGCCAGTCAATTGACACCCTCGAACGTGT
TATTGAAAAAAATAAATACGAGCTCTCTGATAATGAACTGGCGGTATTTTATTCAGCTGCCGACCATCGTCTGGCTGAAC
TAACCATGAATAAACTGTATGACAAGATCCCCTCTTCGGTATGGAAATTTGTTCGTTAA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8535.59 Da        Isoelectric Point: 4.2614

>AT211990 WP_258602840.1 NZ_CP080524:c5264107-5263886 [Mesorhizobium sp. AR10]
MPTSIRLAPEIEERLDFLANKTGRSKAYYLRELIERGLEDVEDYYLAAEVLERIRSGEEEVVKAEDFWRGLDA

Download         Length: 222 bp

>AT211990 NZ_CP106894:c1116643-1116269 [Enterobacter hormaechei]
ATGGACGAGTACTCGCCAAAAAGGCATGATATCGCGCAGTTGAAATTTCTCTGCGAATCCTTGTACCATGACTGCCTTGC
CAATCTTGAAGAAAGTAACCATGGCTGGGTGAACGATCCAACGTCTGCTATCAATTTACAGCTTAACGAGCTGATCGAGC
ATATCGCCACCTTCGCACTTAATTATAAAATTAAGTACAATGAAGATAATAAGTTGATAGAGCAAATTGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTACGGCATTAACGCACAGGATTTGCAGAAATGGCGTAAATCAGGAAACCGCCT
ATTTCGCTGCTTCACCAATGTCAGCAGAGCTAATCCGGTTAGTCTTTCCTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References