Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 4938124..4938716 Replicon chromosome
Accession NZ_CP080524
Organism Mesorhizobium sp. AR10

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LHFGNBLO_RS27650 Protein ID WP_258602450.1
Coordinates 4938124..4938411 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LHFGNBLO_RS27655 Protein ID WP_258602451.1
Coordinates 4938414..4938716 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LHFGNBLO_RS27630 (LHFGNBLO_004790) 4933851..4934675 + 825 WP_258602446.1 MBL fold metallo-hydrolase -
LHFGNBLO_RS27635 (LHFGNBLO_004791) 4934672..4935928 + 1257 WP_258602447.1 CoF synthetase -
LHFGNBLO_RS27640 (LHFGNBLO_004792) 4935925..4937070 + 1146 WP_258602448.1 GNAT family N-acetyltransferase -
LHFGNBLO_RS27645 (LHFGNBLO_004793) 4937067..4938071 + 1005 WP_258602449.1 Rieske 2Fe-2S domain-containing protein -
LHFGNBLO_RS27650 (LHFGNBLO_004794) 4938124..4938411 + 288 WP_258602450.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LHFGNBLO_RS27655 (LHFGNBLO_004795) 4938414..4938716 + 303 WP_258602451.1 putative addiction module antidote protein Antitoxin
LHFGNBLO_RS27660 (LHFGNBLO_004796) 4938718..4939884 - 1167 WP_258602452.1 hypothetical protein -
LHFGNBLO_RS27665 (LHFGNBLO_004797) 4939930..4940481 - 552 WP_258602453.1 isochorismatase family protein -
LHFGNBLO_RS27670 (LHFGNBLO_004798) 4940572..4941315 - 744 WP_258602454.1 hypothetical protein -
LHFGNBLO_RS27675 (LHFGNBLO_004799) 4941463..4943490 - 2028 WP_258602455.1 amidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-94)

Antitoxin

Uncharacterized protein HI1420

(4-94)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10651.45 Da        Isoelectric Point: 10.3368

>T211989 WP_258602450.1 NZ_CP080524:4938124-4938411 [Mesorhizobium sp. AR10]
MIDVRLTADFTKWLDSLRDTAARLRVVARIRRVEIGNIGDAKYFDGIGELRIDHGPGYRVYFVKIGSAVIILLCGGDKST
QKRDIAKAKQMAKDI

Download         Length: 288 bp

>T211989 NZ_CP106894:c299254-298952 [Enterobacter hormaechei]
ATGAAGGAGATCGTTCAGACAGAATCCTTCCGACGCTGGGAGCAAAATTTAAAGGACAGGCGGGCAAAGACGATTATCGC
TTCCCGCCTCTTTAGGCTGGCAAATGGCTTAGCGGGCGACATTAGACCCGTGGGGGAAGGTATCAGTGAACTGAGGATCC
ACTTTGGCCCGGGCTACAGAGTCTATTTTAAGGACCAGGGCAATTGCATCATCGTGCTGTTATGTGGTGGTGACAAAAGC
AGCCAGGCCAGAGACATACTTATGGCAAAAATGCTGAGCAATGTATCCCAATGGCAGGAGTGA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10752.38 Da        Isoelectric Point: 5.1007

>AT211989 WP_258602451.1 NZ_CP080524:4938414-4938716 [Mesorhizobium sp. AR10]
MPLETTRFDILEYLKTPEHRLAYIEAAFEDGDPALITHALGDVARSIGMTAVAKEAGVTREALYKALSDKGDPRLSTLLG
VTKALGLQLYAKPVDPVSAP

Download         Length: 303 bp

>AT211989 NZ_CP106894:c298945-298658 [Enterobacter hormaechei]
ATGCATAAATTAACACCCTACGATCCAGCCAGCGCACTGGTGGATGACGAGGAAATCGCTGTGTTTATGGCTGATGCATT
AGAGACGGGTGACTCAGCGTACATTGCTAAAGCGCTGGGCGTCATCGCCCGAGCGAAAGGGATGTCGACCATTTCCCAGC
AAACGGGCCTGTCACGAGAACAACTGTATCGATCATTCAGTGATAAGGGGAACCCAACGCTCAAAACCACGCTGGCGGTC
ATGAAAGCATTGGGCCTTGGGTTAACAATCAAACCCTCTGGGGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References