211988

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2522922..2523551 Replicon chromosome
Accession NZ_CP080524
Organism Mesorhizobium sp. AR10

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LHFGNBLO_RS15780 Protein ID WP_258608824.1
Coordinates 2523165..2523551 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LHFGNBLO_RS15775 Protein ID WP_258608823.1
Coordinates 2522922..2523155 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LHFGNBLO_RS15750 (LHFGNBLO_002423) 2518846..2519934 - 1089 WP_258608818.1 AbrB family transcriptional regulator -
LHFGNBLO_RS15755 (LHFGNBLO_002424) 2520017..2520325 - 309 WP_258608819.1 putative quinol monooxygenase -
LHFGNBLO_RS15760 (LHFGNBLO_002425) 2520377..2521162 - 786 WP_258608820.1 SDR family oxidoreductase -
LHFGNBLO_RS15765 (LHFGNBLO_002426) 2521226..2521663 - 438 WP_258608821.1 DsrE family protein -
LHFGNBLO_RS15770 (LHFGNBLO_002427) 2521763..2522842 + 1080 WP_258608822.1 hypothetical protein -
LHFGNBLO_RS15775 (LHFGNBLO_002428) 2522922..2523155 + 234 WP_258608823.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
LHFGNBLO_RS15780 (LHFGNBLO_002429) 2523165..2523551 + 387 WP_258608824.1 type II toxin-antitoxin system VapC family toxin Toxin
LHFGNBLO_RS15785 (LHFGNBLO_002430) 2523558..2524505 - 948 WP_258608825.1 cation diffusion facilitator family transporter -
LHFGNBLO_RS15790 (LHFGNBLO_002431) 2524511..2526700 - 2190 WP_258608826.1 anthranilate synthase -
LHFGNBLO_RS15795 (LHFGNBLO_002432) 2527037..2527807 + 771 WP_258608827.1 isocitrate lyase/phosphoenolpyruvate mutase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-121)

Antitoxin

SpoVT-AbrB domain

(7-43)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14313.42 Da        Isoelectric Point: 6.8815

>T211988 WP_258608824.1 NZ_CP080524:2523165-2523551 [Mesorhizobium sp. AR10]
VIYLLDTNAVIAIMKGDADLLARLKHHRPQDFALSAIVVHELYYGAEKSQRKADNLARIEALQFPVLEFDREDARHAGEI
LATLATSGTPIGPYDALVGGQARARNLTLMTRNVREFARIKDLTIETW

Download         Length: 387 bp

>T211988 NZ_CP106894:c298945-298658 [Enterobacter hormaechei]
ATGCATAAATTAACACCCTACGATCCAGCCAGCGCACTGGTGGATGACGAGGAAATCGCTGTGTTTATGGCTGATGCATT
AGAGACGGGTGACTCAGCGTACATTGCTAAAGCGCTGGGCGTCATCGCCCGAGCGAAAGGGATGTCGACCATTTCCCAGC
AAACGGGCCTGTCACGAGAACAACTGTATCGATCATTCAGTGATAAGGGGAACCCAACGCTCAAAACCACGCTGGCGGTC
ATGAAAGCATTGGGCCTTGGGTTAACAATCAAACCCTCTGGGGATTAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8799.83 Da        Isoelectric Point: 4.8096

>AT211988 WP_258608823.1 NZ_CP080524:2522922-2523155 [Mesorhizobium sp. AR10]
VEKAKVFWSGRSQAVRLPKEFRFESEEVSIRRHGQSVILEPLAQDWAWLDQVTGTLDDDFAKAALERPGEQDRPAFG

Download         Length: 234 bp

>AT211988 NZ_CP106894:c299254-298952 [Enterobacter hormaechei]
ATGAAGGAGATCGTTCAGACAGAATCCTTCCGACGCTGGGAGCAAAATTTAAAGGACAGGCGGGCAAAGACGATTATCGC
TTCCCGCCTCTTTAGGCTGGCAAATGGCTTAGCGGGCGACATTAGACCCGTGGGGGAAGGTATCAGTGAACTGAGGATCC
ACTTTGGCCCGGGCTACAGAGTCTATTTTAAGGACCAGGGCAATTGCATCATCGTGCTGTTATGTGGTGGTGACAAAAGC
AGCCAGGCCAGAGACATACTTATGGCAAAAATGCTGAGCAATGTATCCCAATGGCAGGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References