Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1018636..1019174 Replicon chromosome
Accession NZ_CP080512
Organism Pseudomonas protegens strain CM-YJ10_15-44

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag K1T36_RS04535 Protein ID WP_220223703.1
Coordinates 1018896..1019174 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7U9L9U0
Locus tag K1T36_RS04530 Protein ID WP_047283908.1
Coordinates 1018636..1018899 (+) Length 88 a.a.

Genomic Context

K1T36_RS04520K1T36_RS04525K1T36_RS04530K1T36_RS04535K1T36_RS04515K1T36_RS04540K1T36_RS04545K1T36_RS04550K1T36_RS04555
Location: 1017111..1017791 (681 bp)
Type: Others
Protein ID: WP_011059221.1
Location: 1017795..1018580 (786 bp)
Type: Others
Protein ID: WP_077933345.1
Location: 1018636..1018899 (264 bp)
Type: Antitoxin
Protein ID: WP_047283908.1
Location: 1018896..1019174 (279 bp)
Type: Toxin
Protein ID: WP_220223703.1
Location: 1014619..1016904 (2286 bp)
Type: Others
Protein ID: WP_220223702.1
Location: 1019245..1020408 (1164 bp)
Type: Others
Protein ID: WP_015634137.1
Location: 1021087..1022244 (1158 bp)
Type: Others
Protein ID: WP_015634138.1
Location: 1022241..1022894 (654 bp)
Type: Others
Protein ID: WP_011059225.1
Location: 1022907..1023800 (894 bp)
Type: Others
Protein ID: WP_015634139.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
K1T36_RS04515 (K1T36_04515)1014619..1016904-2286WP_220223702.1TonB-dependent siderophore receptor-
K1T36_RS04520 (K1T36_04520)1017111..1017791+681WP_011059221.1Fe2+-dependent dioxygenase-
K1T36_RS04525 (K1T36_04525)1017795..1018580+786WP_077933345.1tetratricopeptide repeat protein-
K1T36_RS04530 (K1T36_04530)1018636..1018899+264WP_047283908.1ribbon-helix-helix domain-containing proteinAntitoxin
K1T36_RS04535 (K1T36_04535)1018896..1019174+279WP_220223703.1type II toxin-antitoxin system RelE/ParE family toxinToxin
K1T36_RS04540 (K1T36_04540)1019245..1020408-1164WP_015634137.1type III PLP-dependent enzyme-
K1T36_RS04545 (K1T36_04545)1021087..1022244-1158WP_015634138.1ABC transporter ATP-binding protein-
K1T36_RS04550 (K1T36_04550)1022241..1022894-654WP_011059225.1ABC transporter permease-
K1T36_RS04555 (K1T36_04555)1022907..1023800-894WP_015634139.1glycine betaine ABC transporter substrate-binding protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-44)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10724.37 Da        Isoelectric Point: 10.2944

>T211972 WP_220223703.1 NZ_CP080512:1018896-1019174 [Pseudomonas protegens]
MRQLKWTSKALSDLARLFEFLAQANRSTAARTVQSLVQAPDALLSNPRLGEQLEEFKPRDVRRLLVGHYEMRYEIQGMAL
SILSIWHVREDR

Download         Length: 279 bp

>T211972 NZ_CP106888:c85185-84880 [Klebsiella pneumoniae]
ATGCAGTTCACCGTCTACGAATACACACGCGAGAGCCATTATCGTCTTTTTGTGGATGTGCAGAGCGACATTGTCGAGAC
GCCTGGGCGACGCATAGTGATCCCGTTGCTGGAATCGCACCACTTATCAGAAAAGGTTAATCAGCAGCTTTTCCCGGTGG
TTAGCGTCAATGGGAAAGAATACCGTGCCGTGACTTCCGAATTATCCGGAGTCTCTGTCAGTGTCATCGGCGACGCTGTG
GCCGATCTCAGCCATGAGGCAAATGCCATTAAAAATGCCCTGAACCTGATGTTCTGGGGCATTTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9676.08 Da        Isoelectric Point: 5.6706

>AT211972 WP_047283908.1 NZ_CP080512:1018636-1018899 [Pseudomonas protegens]
MPATKVLTAHIPLDLADKVDQLASRLERSRAWVVKQALVAWVDQEEERRRLTLEALADVDAGRVVDHQSVLAWAQSLSGD
NPLPLPK

Download         Length: 264 bp

>AT211972 NZ_CP106888:c85403-85185 [Klebsiella pneumoniae]
ATGAAACACAGAGCCAGCGTCACAGTAGACAAGGAACATTATCTGGAATTACTCGCGGCAGGCGTGAATATTTCGGGACT
GGTGAATGAGGCTATCGGACGGGAAGCCCGGCGCATCCAGGCTGAACGCTGGAAAGCAGAGAACCGGGAAGGGATGGAAG
AGGTAGCGAATTTCATCGCGCAGCACGGCTCTTTTGCCGACGAAAACCGGAGCTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A7U9L9U0

References