Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3075641..3076887 Replicon chromosome
Accession NZ_CP080494
Organism Pseudomonas sp. So3.2b

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag K1X80_RS13745 Protein ID WP_186625930.1
Coordinates 3076306..3076887 (+) Length 194 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag K1X80_RS13740 Protein ID WP_220172946.1
Coordinates 3075641..3076198 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K1X80_RS13715 (K1X80_13715) 3070858..3071253 - 396 WP_220172944.1 hypothetical protein -
K1X80_RS13720 (K1X80_13720) 3071646..3072035 + 390 WP_120732971.1 MerR family transcriptional regulator -
K1X80_RS13725 (K1X80_13725) 3072001..3072981 - 981 WP_169990097.1 NAD-dependent epimerase/dehydratase family protein -
K1X80_RS13730 (K1X80_13730) 3073154..3073693 + 540 WP_128593670.1 adenylate kinase -
K1X80_RS13735 (K1X80_13735) 3073871..3075484 + 1614 WP_220172945.1 methyl-accepting chemotaxis protein -
K1X80_RS13740 (K1X80_13740) 3075641..3076198 + 558 WP_220172946.1 helix-turn-helix transcriptional regulator Antitoxin
K1X80_RS13745 (K1X80_13745) 3076306..3076887 + 582 WP_186625930.1 HD domain-containing protein Toxin
K1X80_RS28185 3076884..3077018 - 135 WP_225923873.1 helix-turn-helix domain-containing protein -
K1X80_RS13755 (K1X80_13755) 3077536..3078390 + 855 WP_128593695.1 EamA family transporter -
K1X80_RS13760 (K1X80_13760) 3078653..3079138 + 486 WP_057959725.1 ATP-binding protein -
K1X80_RS13765 (K1X80_13765) 3079190..3080356 - 1167 WP_186625929.1 MFS transporter -
K1X80_RS13770 (K1X80_13770) 3080451..3081344 + 894 WP_057438414.1 LysR substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(9-150)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-64)


Sequences

Toxin        


Download         Length: 194 a.a.        Molecular weight: 21879.83 Da        Isoelectric Point: 4.7722

>T211952 WP_186625930.1 NZ_CP080494:3076306-3076887 [Pseudomonas sp. So3.2b]
MDIEKIKGRLEFLREAEKLKDVLRSAHTSCGRTESTAEHSWRLCLMAIVFGDYLTDLDRLKMLKMCVIHDLGEAINGDVP
AVNQDSFPNKSEQERNDLLLLTSALDEPLKAEILALWDDYENASSPEAVAVKALDKLETMLQHNQGKNPTGFDYEFNLAY
GKKYTDAAPLFEVLRTIIDQETKEHILANSKNH

Download         Length: 582 bp

>T211952 NZ_CP106885:c566629-565316 [Achromobacter spanius]
ATGAACGGCGAATTCGTCGGCACCTGGAGCGTGCAACCGCATGTCGGAGAAGTCCTGCAGTATGCCGACGCCTGGGTGGC
ATCCGGACAGGGGCGCCCGCTGTCGCTGTCCCTCCCCTTCACCCCGGGCAATCCGCCGCACCGTGGCGAAGCCGTGCGCA
CCTACTTCGAAAACCTGCTGCCGGACAGCAAGGAAATCCGCGAGCGCGTGGCACGTCGGTACCAGGCCGGCTCGACCAAT
GCGTTCGCCTTGCTGGCTGAAGTTGGTCGGGACTGTGTCGGCGCGCTGCAGGTGGTGCCGGGCCCCGATGCGCCGGACGG
CGTGCAAGAGGTGAACGCGGTTCCGATGACCGACGCCGAGATTGCCCAGCTGCTTCGCAACACCCTGGCGCCAGGCCCCC
TGGGCCGGAACGCTGCCGAGGATGAAGACTTCCGCATCTCCATTGCCGGAGCACAGGAAAAGTCGGCCATGCTCTGGTAC
GACGGGCGGTGGTGCCGGCCGCATGGCGCGACACCGACCACTCACATCTTCAAGCTGCCACTGGGCCTGGTCGCAAACAT
GAAGTTCGACATGAGCGATTCGGTCGAAAACGAGTGGCTGTGCTCCGAAATCCTGCGCGCCTACCAAATGCCTGTGGCGC
GCACCGAGCCCCTGATGTTCGAGGACATGAAGGTGCTGGCGGTCGAGCGCTTCGACCGGATGTGGTGGGAGAGCCCAGAG
GGCAAGCGCTGGCTCATCCGGCTGCCGCAGGAAGACATGTGCCAAGCGACGGCAACCCCGCCGCATTTGAAGTACGAGTC
CGACGGCGGGCCGGGTGTGCGCCAAATCATGAAGCTGTTGGCTACGTCGCGCGCGCCTGACCGCGACCGTCGCACGTTCT
TCCAGGCCCAGGTCCTCTTCTGGATGCTGCGTGCCACGGATGGCCACGCGAAGAACTTCAGCATTTTCCTGCGCCAGGGT
GGCACCTACGAACTCACCCCGCTGTACGACGTACTTTCCGCTTACCCCGTCATCGGCAAGGGTGCGAAAAAGCTGTCTCC
GTACGACGCCAAGATGGCCATGGCCGTGCGCTCGAAAAACCCCCACTGGGTCATGCGCGACATCCTGCGTCGGCACTGGA
TCGCCGTGGGCACCGAGCATGGCGTAGTGAATCCCGACGGTAAGGGGGTGGAGCATGTCCTCGACGACCTGGTGGCGCGC
ACGCCCGGGGTCGTGAAGGCCGTCCGCGCGCTACTGCCGGCGGGATTCCCCATGCACGTGGCCGACTGCATCCTCAACGG
CCTGCAAGAGGCCGCTGACCACCTGGCAGGTTAG

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20704.09 Da        Isoelectric Point: 9.6396

>AT211952 WP_220172946.1 NZ_CP080494:3075641-3076198 [Pseudomonas sp. So3.2b]
MSDMLLSPVLPGVMLRRWRLLHRVKQSHAAELFNVTQSTISRWESGVLELDPLAHKKLEQLLAARLTTAADQALGRMVRE
SSRPVHLMCDLTHRLLACSPSRAAQFTSPVSELLGRSLWRFATPNIISNELALDKLGWREAFAPPALEFLTGHNNSSIVP
ISQSLCRWTRMPLCDGTTARLVESL

Download         Length: 558 bp

>AT211952 NZ_CP106885:c566933-566673 [Achromobacter spanius]
ATGACCGATTTCACCGTCCGTACGGCGGAGCAGCTGCCTGCACTGCTCCAGGGTTTTCGCAAACAGTCCGGCCTGACCCA
AGCGGATACGGCGATGCGCCTGGGCGTCAGCCAGCAGGCCTTGTCTCATCTCGAGCGCCATGCCGACAAGGTCAGCGCCG
ACCGCCTGCTGGAGCTTCTGAGCATCCTGGGCGTCGAGCTCGTGCTGCGCAAGACCAGCGAATCGCCGTCGCCCAAGGCG
TCGGTTGGCCCCAACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References