Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 77035..77665 Replicon chromosome
Accession NZ_CP080491
Organism Microbacterium sp. Se5.02b

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag K1X59_RS00410 Protein ID WP_220173820.1
Coordinates 77035..77451 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag K1X59_RS00415 Protein ID WP_244632278.1
Coordinates 77435..77665 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K1X59_RS00385 (K1X59_00385) 73092..73397 - 306 WP_220173818.1 hypothetical protein -
K1X59_RS00390 (K1X59_00390) 73388..73936 - 549 WP_220173819.1 hypothetical protein -
K1X59_RS00395 (K1X59_00395) 73933..74579 - 647 Protein_76 TetR/AcrR family transcriptional regulator -
K1X59_RS00400 (K1X59_00400) 74789..75508 + 720 WP_244632277.1 GntR family transcriptional regulator -
K1X59_RS00405 (K1X59_00405) 75533..76978 - 1446 WP_183151440.1 argininosuccinate synthase -
K1X59_RS00410 (K1X59_00410) 77035..77451 - 417 WP_220173820.1 PIN domain-containing protein Toxin
K1X59_RS00415 (K1X59_00415) 77435..77665 - 231 WP_244632278.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
K1X59_RS00420 (K1X59_00420) 77908..78585 + 678 WP_244632279.1 hypothetical protein -
K1X59_RS00425 (K1X59_00425) 78586..78975 - 390 WP_183151442.1 pyridoxamine 5'-phosphate oxidase family protein -
K1X59_RS00430 (K1X59_00430) 79196..81361 + 2166 WP_183151443.1 RICIN domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-123)

Antitoxin

SpoVT-AbrB domain

(3-40)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14347.46 Da        Isoelectric Point: 6.4783

>T211947 WP_220173820.1 NZ_CP080491:c77451-77035 [Microbacterium sp. Se5.02b]
MPTSADLLLDTSAALALIHDMNPAHEQVRLRTKDLRLGLAGHAAFETYSVLTRMPGAARVTPARAVEIIERAFPSSVALS
SAAALSAVRTLSEAGISGGAVYDGLVGLAAREADIPLVTCDRRAIGTYAALQVDAHVV

Download         Length: 417 bp

>T211947 NZ_CP106874:c4531395-4531093 [Shewanella xiamenensis]
ATGGCTGAAATAATTTGGACGGAACCTGCTTTAGCTGATCTGAATGATATTGCTGAATATATCGCACTTGAAAATATCGT
TGCTGCCAAGCAACTGGTTCAAATGGTTTTTGCAAAGGTTGAGCGTTTAGTTGATTTTCCCGATTCTGGGCGTATTCCAC
CAGAACTAGAGCGGCTCAATTATCGTGAAGTAGTGGTAAATCCATGTCGTGTTTTTTACAAGTATGACGATGAAAAGGTT
CGAATTCTTTTTGTTATGCGTGCGGAAAGAGATTTGCGCCGTTTTATGCTGACGAAACAGTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8268.63 Da        Isoelectric Point: 4.7420

>AT211947 WP_244632278.1 NZ_CP080491:c77665-77435 [Microbacterium sp. Se5.02b]
MKATMDKAGRIVIPAQLRERVGLVPGPVDLILDGNGIRIEIEAPDNVIEKDGRLVITGGPVLTVDDVRELRLADQR

Download         Length: 231 bp

>AT211947 NZ_CP106874:c4531640-4531383 [Shewanella xiamenensis]
ATGAAAGTGGAACTCGTGACGTCACTAAAACGTCAAGCAACTAAGATCCTTGCCGATCTGCATGAGACCAAAGAACCAGT
ATTAATTACTGAGCATGGTAAACCGTCAGCTTATCTTATTGATGTAGAAGATTATGAGTTTATGCAAAATCGTTTGGCGA
TTCTTGAAGGTATTGCACGTGGTGAGCGAGCTTTAGCGGATGGAAAAGTCGTCAGCCATCAAGATGCTAAGGACAGAATG
TCAAAATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References