21190

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4730936..4731299 Replicon chromosome
Accession NC_007086
Organism Xanthomonas campestris pv. campestris str. 8004

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag XC_RS20300 Protein ID WP_011270059.1
Coordinates 4730936..4731070 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag XC_RS20305 Protein ID WP_011038999.1
Coordinates 4731147..4731299 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XC_RS20280 4726200..4727852 - 1653 WP_043877841.1 M28 family peptidase -
XC_RS20285 4728017..4728961 - 945 WP_043877842.1 MBL fold metallo-hydrolase -
XC_RS20290 4729045..4730334 - 1290 WP_043877944.1 tryptophan--tRNA ligase -
XC_RS20295 4730494..4730703 - 210 WP_011038998.1 CsbD family protein -
XC_RS20300 4730936..4731070 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
XC_RS20305 4731147..4731299 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
XC_RS20310 4731410..4732333 - 924 WP_011039000.1 arginase -
XC_RS20315 4732647..4733108 + 462 WP_011039001.1 roadblock/LC7 domain-containing protein -
XC_RS20320 4733191..4733550 + 360 WP_011039002.1 hypothetical protein -
XC_RS20325 4733653..4734570 + 918 WP_011039003.1 hypothetical protein -
XC_RS20330 4734567..4735109 + 543 WP_011039004.1 GTPase -
XC_RS20335 4735444..4736127 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T21190 WP_011270059.1 NC_007086:c4731070-4730936 [Xanthomonas campestris pv. campestris str. 8004]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T21190 NC_007086:c4731070-4730936 [Xanthomonas campestris pv. campestris str. 8004]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTTGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT21190 WP_011038999.1 NC_007086:c4731299-4731147 [Xanthomonas campestris pv. campestris str. 8004]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT21190 NC_007086:c4731299-4731147 [Xanthomonas campestris pv. campestris str. 8004]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0


Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References