Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | EcnAB/- |
Location | 4730936..4731299 | Replicon | chromosome |
Accession | NC_007086 | ||
Organism | Xanthomonas campestris pv. campestris str. 8004 |
Toxin (Protein)
Gene name | EcnB | Uniprot ID | G0CKD4 |
Locus tag | XC_RS20300 | Protein ID | WP_011270059.1 |
Coordinates | 4730936..4731070 (-) | Length | 45 a.a. |
Antitoxin (Protein)
Gene name | EcnA | Uniprot ID | Q8P3Z2 |
Locus tag | XC_RS20305 | Protein ID | WP_011038999.1 |
Coordinates | 4731147..4731299 (-) | Length | 51 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
XC_RS20280 | 4726200..4727852 | - | 1653 | WP_043877841.1 | M28 family peptidase | - |
XC_RS20285 | 4728017..4728961 | - | 945 | WP_043877842.1 | MBL fold metallo-hydrolase | - |
XC_RS20290 | 4729045..4730334 | - | 1290 | WP_043877944.1 | tryptophan--tRNA ligase | - |
XC_RS20295 | 4730494..4730703 | - | 210 | WP_011038998.1 | CsbD family protein | - |
XC_RS20300 | 4730936..4731070 | - | 135 | WP_011270059.1 | entericidin A/B family lipoprotein | Toxin |
XC_RS20305 | 4731147..4731299 | - | 153 | WP_011038999.1 | entericidin A/B family lipoprotein | Antitoxin |
XC_RS20310 | 4731410..4732333 | - | 924 | WP_011039000.1 | arginase | - |
XC_RS20315 | 4732647..4733108 | + | 462 | WP_011039001.1 | roadblock/LC7 domain-containing protein | - |
XC_RS20320 | 4733191..4733550 | + | 360 | WP_011039002.1 | hypothetical protein | - |
XC_RS20325 | 4733653..4734570 | + | 918 | WP_011039003.1 | hypothetical protein | - |
XC_RS20330 | 4734567..4735109 | + | 543 | WP_011039004.1 | GTPase | - |
XC_RS20335 | 4735444..4736127 | + | 684 | WP_011039005.1 | dTMP kinase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 45 a.a. Molecular weight: 4431.27 Da Isoelectric Point: 9.3487
>T21190 WP_011270059.1 NC_007086:c4731070-4730936 [Xanthomonas campestris pv. campestris str. 8004]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK
Download Length: 135 bp
>T21190 NC_007086:c4731070-4730936 [Xanthomonas campestris pv. campestris str. 8004]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTTGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTTGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA
Antitoxin
Download Length: 51 a.a. Molecular weight: 5173.15 Da Isoelectric Point: 8.2782
>AT21190 WP_011038999.1 NC_007086:c4731299-4731147 [Xanthomonas campestris pv. campestris str. 8004]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC
Download Length: 153 bp
>AT21190 NC_007086:c4731299-4731147 [Xanthomonas campestris pv. campestris str. 8004]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTAA
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0H2XDQ0 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | Q8P3Z2 |