Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 984381..985180 Replicon chromosome
Accession NZ_CP080421
Organism Shewanella mesophila strain FJAT-53870

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag K0I73_RS04385 Protein ID WP_220063312.1
Coordinates 984647..985180 (+) Length 178 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag K0I73_RS04380 Protein ID WP_220063311.1
Coordinates 984381..984650 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K0I73_RS04370 (K0I73_04370) 980654..981535 + 882 WP_220063309.1 mechanosensitive ion channel -
K0I73_RS04375 (K0I73_04375) 981616..982971 - 1356 WP_220063310.1 magnesium transporter -
K0I73_RS04380 (K0I73_04380) 984381..984650 + 270 WP_220063311.1 DUF1778 domain-containing protein Antitoxin
K0I73_RS04385 (K0I73_04385) 984647..985180 + 534 WP_220063312.1 GNAT family N-acetyltransferase Toxin
K0I73_RS04390 (K0I73_04390) 985414..986564 + 1151 WP_220063313.1 IS3 family transposase -
K0I73_RS04395 (K0I73_04395) 986642..986920 - 279 WP_220063314.1 peptidylprolyl isomerase PpiC -
K0I73_RS04400 (K0I73_04400) 987156..988049 + 894 WP_220063315.1 LysR family transcriptional regulator -
K0I73_RS04405 (K0I73_04405) 988132..988701 - 570 WP_220063316.1 LUD domain-containing protein -
K0I73_RS04410 (K0I73_04410) 988703..990094 - 1392 WP_220063317.1 lactate utilization protein B -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(97-153)

Antitoxin

Vibrio phage ICP1, Orf50

(5-81)


Sequences

Toxin        


Download         Length: 178 a.a.        Molecular weight: 20112.39 Da        Isoelectric Point: 9.1189

>T211875 WP_220063312.1 NZ_CP080421:984647-985180 [Shewanella mesophila]
VSWGKEFVELSKSYHDRNSFDCGEQELNTFIKTQAAKHMEAGISRTMILPSAQPLLNQKFAICAFYSVAPSSISRETLPA
QLAKKLPRYPIPVFLLAQLAVHKEFHGSGLGKVSLIRALKYLWEVNHHMRAYAIVVDCLTDSAQAFYTKFGFEVLCEHNG
RIRMFLPMKTVETLFNQ

Download         Length: 534 bp

>T211875 NZ_CP106815:657162-657581 [Neisseria gonorrhoeae]
ATGATTTTGCTGGACACGAATGTGATTTCCGAACCTTTGCGCCCACAACCCAATGAACGTGTGGTGGCATGGTTGGATAG
TTTGATATTGGAAGATGTGTATTTGTCTGCCATTACTGTTGCAGAATTGCGTTTGGGTGTGGCGTTGTTGCTCAATGGCA
AGAAAAAGAATGTGCTGCACGAACGTTTGGAACAATCCATTTTGCCTTTATTTGCGGGGTGGATTCTGCCTTTTGATGAA
CCGGTTGCCGCAATCTATGCGCAAATTCGTTCCTATGCCAAAACACATGGCAAAGAGATTGCTGCCGCAGACGGCTATAT
TGCCGCCACTGCAAAACAGCACAGTTTGACAGTTGCTACGCGTGATACCGGCTCATTTTTTGCGGCCGATGTCGCGGTGT
TCAATCCGTGGCACGATTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9732.13 Da        Isoelectric Point: 4.4442

>AT211875 WP_220063311.1 NZ_CP080421:984381-984650 [Shewanella mesophila]
MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDATHVIEEHESIVVQDSVFDAFMAACDKAKAPNQALLEAA
KLTDESGIK

Download         Length: 270 bp

>AT211875 NZ_CP106815:656926-657162 [Neisseria gonorrhoeae]
ATGGCTTCTGTTGTGATTAGAAATTTATCCGAGGCCACGCACAACGCAATCAAATTCCGTGCGCGAGCCGCAGGGCGCAG
TACCGAAGCAGAAATCCGCTTAATTTTGGATAACATCGCCAAAGCACAACAAACTGTACGTTTGGGGTCAATGTTGGCAT
CAATAGGGCAGGAAATCGGAGGTGTTGAGCTGGAAGACGTACGCGGTCGTAATACTGATAACGAGGTTTCTTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References