Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ygfYX/Cpta(toxin)
Location 1188761..1189436 Replicon chromosome
Accession NZ_CP080420
Organism Shewanella rhizosphaerae strain FJAT-53764

Toxin (Protein)


Gene name ygfX Uniprot ID -
Locus tag K0I63_RS05295 Protein ID WP_220082777.1
Coordinates 1188981..1189436 (+) Length 152 a.a.

Antitoxin (Protein)


Gene name ygfY Uniprot ID -
Locus tag K0I63_RS05290 Protein ID WP_220073918.1
Coordinates 1188761..1189000 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K0I63_RS05265 (K0I63_05265) 1184132..1184926 + 795 WP_220082774.1 sulfite exporter TauE/SafE family protein -
K0I63_RS05270 (K0I63_05270) 1185042..1185893 + 852 WP_220082775.1 thymidylate synthase -
K0I63_RS05275 (K0I63_05275) 1186200..1187375 + 1176 WP_011864846.1 Na+/H+ antiporter NhaA -
K0I63_RS05280 (K0I63_05280) 1187372..1187755 + 384 WP_220082776.1 hypothetical protein -
K0I63_RS05285 (K0I63_05285) 1187776..1188684 + 909 WP_011864848.1 transcriptional activator NhaR -
K0I63_RS05290 (K0I63_05290) 1188761..1189000 + 240 WP_220073918.1 succinate dehydrogenase assembly factor 2 Antitoxin
K0I63_RS05295 (K0I63_05295) 1188981..1189436 + 456 WP_220082777.1 hypothetical protein Toxin
K0I63_RS05300 (K0I63_05300) 1189445..1191058 - 1614 WP_011864851.1 L-aspartate oxidase -
K0I63_RS05305 (K0I63_05305) 1191258..1191836 + 579 WP_011864852.1 RNA polymerase sigma factor RpoE -
K0I63_RS05310 (K0I63_05310) 1191876..1192478 + 603 WP_011864853.1 RseA family anti-sigma factor -
K0I63_RS05315 (K0I63_05315) 1192544..1193476 + 933 WP_220082778.1 MucB/RseB C-terminal domain-containing protein -
K0I63_RS05320 (K0I63_05320) 1193484..1193960 + 477 WP_220082779.1 SoxR reducing system RseC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(5-149)

Antitoxin

Flavinator of succinate dehydrogenase

(4-75)


Sequences

Toxin        


Download         Length: 152 a.a.        Molecular weight: 18020.07 Da        Isoelectric Point: 8.7156

>T211874 WP_220082777.1 NZ_CP080420:1188981-1189436 [Shewanella rhizosphaerae]
VAGRRHNFHLTASFDQRLSLVCFAALCLSAFLVWPPITSFWFLTLKYGLLLATISFFLYQFIALRRWSLAFWLDESGRIG
LIRDELDSHTQVQQVEEAIEQQLSYRRIWVSPLVVLFWLYEGERKRLVILWRDMFDDTGYRHLCRLLLRFG

Download         Length: 456 bp

>T211874 NZ_CP106814:1597-1875 [Neisseria gonorrhoeae]
ATGTACGCGATTTCTTTTGATTTGGTGGTTGCCGATACCGCTCAAAACCATCCGAAAGGCATTTCCCAAGCCTACGCGGA
TATTGGATACACCCTGCGGAAATTCGGCTTTACCCGCATTCAGGGAAGTTTGTACACCTGCCAAAACGAAGATATGGCTA
ACCTGTTTTCAGCCATCAACGAGCTAAAAGCTCTGCCTTGGTTTCCGTCTTCTGTCCGCGATATTCGGGCGTTCCGCATT
GAGCAGTGGTCTGATTTCACAAGTCTTGTGAAGTCTTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9183.69 Da        Isoelectric Point: 4.5679

>AT211874 WP_220073918.1 NZ_CP080420:1188761-1189000 [Shewanella rhizosphaerae]
MNIARVRWACRRGMLELDVLFQPFVETQYEQLSIDDKAVFVRLLECEDPELFAWFMGHEACPDPQLAEMVVKVRGRAAP

Download         Length: 240 bp

>AT211874 NZ_CP106814:1412-1597 [Neisseria gonorrhoeae]
ATGCAAACCACTATCCCCACCGGTTCAATCCGCACCTTTGGCGATTACGGCGTGATGTACATCGTCGGCACGCCTGCCGA
ACAGCTTCCGGACGGCGATTGGCTCGTAAATATTGAACTGCCGGAAAGCGGCGAACACACGCAATACAAACTGTCCCACA
TCGTTCAAGACCCAAAGGCTGCCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References