211872

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ygfYX/Cpta(toxin)
Location 1195952..1196627 Replicon chromosome
Accession NZ_CP080418
Organism Shewanella spartinae strain FJAT-53681

Toxin (Protein)


Gene name ygfX Uniprot ID -
Locus tag K0I31_RS05275 Protein ID WP_220080142.1
Coordinates 1196172..1196627 (+) Length 152 a.a.

Antitoxin (Protein)


Gene name ygfY Uniprot ID -
Locus tag K0I31_RS05270 Protein ID WP_220073918.1
Coordinates 1195952..1196191 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K0I31_RS05245 (K0I31_05245) 1191316..1192110 + 795 WP_220080140.1 sulfite exporter TauE/SafE family protein -
K0I31_RS05250 (K0I31_05250) 1192233..1193084 + 852 WP_220080141.1 thymidylate synthase -
K0I31_RS05255 (K0I31_05255) 1193391..1194566 + 1176 WP_011864846.1 Na+/H+ antiporter NhaA -
K0I31_RS05260 (K0I31_05260) 1194563..1194946 + 384 WP_011864847.1 hypothetical protein -
K0I31_RS05265 (K0I31_05265) 1194967..1195875 + 909 WP_011864848.1 transcriptional activator NhaR -
K0I31_RS05270 (K0I31_05270) 1195952..1196191 + 240 WP_220073918.1 succinate dehydrogenase assembly factor 2 Antitoxin
K0I31_RS05275 (K0I31_05275) 1196172..1196627 + 456 WP_220080142.1 hypothetical protein Toxin
K0I31_RS05280 (K0I31_05280) 1196639..1198252 - 1614 WP_011864851.1 L-aspartate oxidase -
K0I31_RS05285 (K0I31_05285) 1198452..1199030 + 579 WP_011864852.1 RNA polymerase sigma factor RpoE -
K0I31_RS05290 (K0I31_05290) 1199070..1199672 + 603 WP_011864853.1 RseA family anti-sigma factor -
K0I31_RS05295 (K0I31_05295) 1199738..1200670 + 933 WP_011864854.1 MucB/RseB C-terminal domain-containing protein -
K0I31_RS05300 (K0I31_05300) 1200678..1201154 + 477 WP_220080143.1 SoxR reducing system RseC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(5-149)

Antitoxin

Flavinator of succinate dehydrogenase

(4-75)


Sequences

Toxin        


Download         Length: 152 a.a.        Molecular weight: 17889.88 Da        Isoelectric Point: 8.2867

>T211872 WP_220080142.1 NZ_CP080418:1196172-1196627 [Shewanella spartinae]
VAGRRHNFHLTASFDQRLSLVCFAALCLSAFLVWPPINSLWFLTLKYGLLLATIVFFLYQLIALRRWSLAFWLDESGRIG
LLRDELDSHTQVQQADEASEQHLSYRRIWVSPLVVLFWLYEGEQKRLVILWRDMFDDTGYRHLCRLLLRFG

Download         Length: 456 bp

>T211872 NZ_CP106813:661546-661965 [Neisseria gonorrhoeae]
ATGATTTTGCTGGACACGAATGTGATTTCCGAACCTTTGCGCCCACAACCCAATGAACGTGTGGTGGCATGGTTGGATAG
TTTGATATTGGAAGATGTGTATTTGTCTGCCATTACTGTTGCAGAATTGCGTTTGGGTGTGGCGTTGTTGCTCAATGGCA
AGAAAAAGAATGTGCTGCACGAACGTTTGGAACAATCCATTTTGCCTTTATTTGCGGGGCGGATTCTGCCTTTTGATGAA
CCGGTTGCCGCAATCTATGCGCAAATTCGTTCCTATGCCAAAACACATGGCAAAGAGATTGCTGCCGCAGACGGCTATAT
TGCCGCCACTGCAAAACAGCACAGTTTGACAGTTGCTACGCGTGATACCGGCTCATTTTTTGCGGCCGATGTCGCGGTGT
TCAATCCGTGGCACGATTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9183.69 Da        Isoelectric Point: 4.5679

>AT211872 WP_220073918.1 NZ_CP080418:1195952-1196191 [Shewanella spartinae]
MNIARVRWACRRGMLELDVLFQPFVETQYEQLSIDDKAVFVRLLECEDPELFAWFMGHEACPDPQLAEMVVKVRGRAAP

Download         Length: 240 bp

>AT211872 NZ_CP106813:661310-661546 [Neisseria gonorrhoeae]
ATGGCTTCTGTTGTGATTAGAAATTTATCCGAGGCCACGCACAACGCAATCAAATTCCGTGCGCGAGCCGCAGGGCGCAG
TACCGAAGCAGAAATCCGCTTAATTTTGGATAACATCGCCAAAGCACAACAAACTGTACGTTTGGGGTCAATGTTGGCAT
CAATAGGGCAGGAAATCGGAGGTGTTGAGCTGGAAGACGTACGCGGTCGTAATACTGATAACGAGGTTTCTTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References