21187

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 4568993..4569518 Replicon chromosome
Accession NC_007005
Organism Pseudomonas syringae pv. syringae B728a

Toxin (Protein)


Gene name stbE Uniprot ID Q4ZPQ9
Locus tag PSYR_RS19835 Protein ID WP_011268681.1
Coordinates 4569228..4569518 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q4ZPR0
Locus tag PSYR_RS19830 Protein ID WP_003402372.1
Coordinates 4568993..4569238 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSYR_RS19825 (Psyr_3831) 4564908..4568819 - 3912 WP_011268680.1 ATP-dependent RNA helicase HrpA -
PSYR_RS19830 (Psyr_3832) 4568993..4569238 + 246 WP_003402372.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PSYR_RS19835 (Psyr_3833) 4569228..4569518 + 291 WP_011268681.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PSYR_RS19840 (Psyr_3834) 4569836..4571527 - 1692 WP_011268682.1 long-chain-fatty-acid--CoA ligase FadD1 -
PSYR_RS19845 (Psyr_3836) 4571883..4573571 - 1689 WP_011268684.1 long-chain-fatty-acid--CoA ligase FadD2 -
PSYR_RS19850 (Psyr_3838) 4573940..4574410 + 471 WP_003402365.1 MaoC family dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-81)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-71)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11010.01 Da        Isoelectric Point: 10.7294

>T21187 WP_011268681.1 NC_007005:4569228-4569518 [Pseudomonas syringae pv. syringae B728a]
MTFKLEFLPSALKEWEKLGHTIRVQLKKKLLERLGLPRIPGDALHGMPDHYKIKLRSAGYRLVYRVEEDRVVVTVVAVGK
RERGNIYDSAKGRLGP

Download         Length: 291 bp

>T21187 NC_007005:4569228-4569518 [Pseudomonas syringae pv. syringae B728a]
ATGACCTTTAAGCTTGAATTTCTGCCCTCGGCCTTGAAGGAGTGGGAAAAACTGGGCCATACCATCCGTGTTCAGCTCAA
GAAAAAGCTTCTCGAACGACTCGGACTACCAAGAATTCCAGGCGATGCGCTTCATGGCATGCCAGATCATTACAAAATCA
AACTGCGCAGTGCAGGATACCGACTCGTCTATCGAGTCGAGGAAGATAGGGTAGTGGTAACCGTCGTTGCGGTAGGCAAG
CGCGAGCGCGGGAATATTTATGATTCGGCCAAAGGCAGGCTTGGCCCTTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8827.22 Da        Isoelectric Point: 4.5349

>AT21187 WP_003402372.1 NC_007005:4568993-4569238 [Pseudomonas syringae pv. syringae B728a]
MQSILADVAVSVSELKKNPSAVLSGAHGLPVAVLNHNKVMGYMVPAEVFEAMMERLDDLDLAELIKSRQHEKPVSVDIDD
L

Download         Length: 246 bp

>AT21187 NC_007005:4568993-4569238 [Pseudomonas syringae pv. syringae B728a]
ATGCAAAGCATCCTTGCAGATGTCGCGGTCAGCGTCTCTGAACTCAAGAAAAATCCGTCAGCGGTCCTGAGTGGCGCTCA
TGGTTTACCTGTGGCCGTCCTTAATCACAATAAAGTCATGGGCTACATGGTCCCTGCCGAGGTGTTTGAAGCAATGATGG
AGAGGCTTGATGACCTTGATCTGGCCGAGCTGATCAAATCTCGCCAACATGAAAAGCCGGTGTCGGTAGATATAGATGAC
CTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q4ZPQ9

Antitoxin

Source ID Structure
AlphaFold DB A0A3M2V2W1

References