Detailed information of TA system TA211869

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ygfYX/Cpta(toxin)
• Location: 1175170..1175845
• Replicon: chromosome
• Accession: NZ_CP080416
• Organism: Shewanella aegiceratis strain FJAT-53532

Toxin (Protein)

• Gene name: ygfX
• Uniprot ID: -
• Locus tag: K0H80_RS05205
• Protein ID: WP_220044545.1
• Coordinates: 1175390..1175845 (+)
• Length: 152 a.a.

Antitoxin (Protein)

• Gene name: ygfY
• Uniprot ID: -
• Locus tag: K0H80_RS05200
• Protein ID: WP_220073918.1
• Coordinates: 1175170..1175409 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K0H80_RS05175 (K0H80_05175)	1170541..1171335	+	795	WP_220073330.1	sulfite exporter TauE/SafE family protein	-
K0H80_RS05180 (K0H80_05180)	1171451..1172302	+	852	WP_144201092.1	thymidylate synthase	-
K0H80_RS05185 (K0H80_05185)	1172609..1173784	+	1176	WP_011864846.1	Na+/H+ antiporter NhaA	-
K0H80_RS05190 (K0H80_05190)	1173781..1174164	+	384	WP_011864847.1	hypothetical protein	-
K0H80_RS05195 (K0H80_05195)	1174185..1175093	+	909	WP_220073331.1	transcriptional activator NhaR	-
K0H80_RS05200 (K0H80_05200)	1175170..1175409	+	240	WP_220073918.1	succinate dehydrogenase assembly factor 2	Antitoxin
K0H80_RS05205 (K0H80_05205)	1175390..1175845	+	456	WP_220044545.1	hypothetical protein	Toxin
K0H80_RS05210 (K0H80_05210)	1175857..1177470	-	1614	WP_011864851.1	L-aspartate oxidase	-
K0H80_RS05215 (K0H80_05215)	1177670..1178248	+	579	WP_011864852.1	RNA polymerase sigma factor RpoE	-
K0H80_RS05220 (K0H80_05220)	1178288..1178890	+	603	WP_011864853.1	RseA family anti-sigma factor	-
K0H80_RS05225 (K0H80_05225)	1178956..1179888	+	933	WP_220073332.1	MucB/RseB C-terminal domain-containing protein	-
K0H80_RS05230 (K0H80_05230)	1179896..1180372	+	477	WP_220073333.1	SoxR reducing system RseC family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (5-149)

Antitoxin

• Flavinator of succinate dehydrogenase (4-75)

Sequences

Toxin

Protein

• Length: 152 a.a.
• Molecular weight: 17898.85 Da
• Isoelectric Point: 8.2867

>T211869 WP_220044545.1 NZ_CP080416:1175390-1175845 [Shewanella aegiceratis]
VAGRRHNFHLTASFDQRLSLVCFAALCLSAFLVWPPIASLWFLTLKYGLLTATITFFLYQFIALRRWSLAFWLDESGRIG
LLRDELDSHTQVQQVDEASEQHLSYRRIWVSPLVVLFWLYEGEQKRLVILWRDMFDDTGYRHLCRLLLRFG

Nucleotide

• Length: 456 bp

>T211869 NZ_CP106811:652483-652902 [Neisseria gonorrhoeae]
ATGATTTTGCTGGACACGAATGTGATTTCCGAACCTTTGCGCCCACAACCCAATGAACGTGTGGTGGCATGGTTGGATAG
TTTGATATTGGAAGATGTGTATTTGTCTGCCATTACTGTTGCAGAATTGCGTTTGGGTGTGGCGTTGTTGCTCAATGGCA
AGAAAAAGAATGTGCTGCACGAACGTTTGGAACAATCCATTTTGCCTTTATTTGCGGGGCGGATTCTGCCTTTTGATGAA
CCGGTTGCCGCAATCTATGCGCAAATTCGTTCCTATGCCAAAACACATGGCAAAGAGATTGCTGCCGCAGACGGCTATAT
TGCCGCCACTGCAAAACAGCACAGTTTGACAGTTGCTACGCGTGATACCGGCTCATTTTTTGCGGCCGATGTCGCGGTGT
TCAATCCGTGGCACGATTAA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 9183.69 Da
• Isoelectric Point: 4.5679

>AT211869 WP_220073918.1 NZ_CP080416:1175170-1175409 [Shewanella aegiceratis]
MNIARVRWACRRGMLELDVLFQPFVETQYEQLSIDDKAVFVRLLECEDPELFAWFMGHEACPDPQLAEMVVKVRGRAAP

Nucleotide

• Length: 240 bp

>AT211869 NZ_CP106811:652247-652483 [Neisseria gonorrhoeae]
ATGGCTTCTGTTGTGATTAGAAATTTATCCGAGGCCACGCACAACGCAATCAAATTCCGTGCGCGAGCCGCAGGGCGCAG
TACCGAAGCAGAAATCCGCTTAATTTTGGATAACATCGCCAAAGCACAACAAACTGTACGTTTGGGGTCAATGTTGGCAT
CAATAGGGCAGGAAATCGGAGGTGTTGAGCTGGAAGACGTACGCGGTCGTAATACTGATAACGAGGTTTCTTTGTGA