Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 3455468..3456559 Replicon chromosome
Accession NZ_CP080415
Organism Shewanella sp. FJAT-52076

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag K0H79_RS15260 Protein ID WP_220076379.1
Coordinates 3455468..3456196 (-) Length 243 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag K0H79_RS15265 Protein ID WP_220065552.1
Coordinates 3456197..3456559 (-) Length 121 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K0H79_RS15235 (K0H79_15235) 3452056..3452475 + 420 WP_220076375.1 CBS domain-containing protein -
K0H79_RS15240 (K0H79_15240) 3452524..3453213 - 690 WP_203324853.1 LrgB family protein -
K0H79_RS15245 (K0H79_15245) 3453213..3453644 - 432 WP_220076376.1 CidA/LrgA family protein -
K0H79_RS15250 (K0H79_15250) 3453748..3454656 + 909 WP_220076377.1 LysR family transcriptional regulator -
K0H79_RS15255 (K0H79_15255) 3454633..3455448 - 816 WP_220076378.1 hypothetical protein -
K0H79_RS15260 (K0H79_15260) 3455468..3456196 - 729 WP_220076379.1 RES family NAD+ phosphorylase Toxin
K0H79_RS15265 (K0H79_15265) 3456197..3456559 - 363 WP_220065552.1 MbcA/ParS/Xre antitoxin family protein Antitoxin
K0H79_RS15270 (K0H79_15270) 3456802..3457455 + 654 WP_220076380.1 oxygen-insensitive NAD(P)H nitroreductase -
K0H79_RS15275 (K0H79_15275) 3457595..3458245 + 651 WP_220065554.1 DNA-J related domain-containing protein -
K0H79_RS15280 (K0H79_15280) 3458405..3459151 + 747 WP_220076381.1 thiol:disulfide interchange protein DsbA/DsbL -
K0H79_RS15285 (K0H79_15285) 3459589..3460926 + 1338 WP_220076382.1 Na+/H+ antiporter NhaC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(50-198)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(69-118)


Sequences

Toxin        


Download         Length: 243 a.a.        Molecular weight: 27761.64 Da        Isoelectric Point: 5.6422

>T211868 WP_220076379.1 NZ_CP080415:c3456196-3455468 [Shewanella sp. FJAT-52076]
MDLLSIPEVPYEGSCYRLVESQEEAATLSLVDNFDEQMLLESLLDGAKPPYREGTAHLHYLLKTPFRYPPLRHGSRFGTR
LMPSFFYGSESVQTCLTEVAYYRFVFLQDMVVPYQGVLHSEHMMFRVLLSAKRCADLTRIADDTLQRQLTHGEDYRFTQA
LGQQLLERDCQLIRSYSAREPGGVNLAVADPGVMASAPLDQSYWICQLEPARLAFTERGRGNMPRYYEVEAFFREGRLPR
PA

Download         Length: 729 bp

>T211868 NZ_CP106810:c2353-2075 [Neisseria gonorrhoeae]
ATGTACGCGATTTCTTTTGATTTGGTGGTTGCCGATACCGCTCAAAACCATCCGAAAGGCATTTCCCAAGCCTACGCGGA
TATTGGATACACCCTGCGGAAATTCGGCTTTACCCGCATTCAGGGAAGTTTGTACACCTGCCAAAACGAAGATATGGCTA
ACCTGTTTTCAGCCATCAACGAGCTAAAAGCTCTGCCTTGGTTTCCGTCTTCTGTCCGCGATATTCGGGCGTTCCGCATT
GAGCAGTGGTCTGATTTCACAAGTCTTGTGAAGTCTTAA

Antitoxin


Download         Length: 121 a.a.        Molecular weight: 12950.90 Da        Isoelectric Point: 10.2283

>AT211868 WP_220065552.1 NZ_CP080415:c3456559-3456197 [Shewanella sp. FJAT-52076]
MSAIAKPTASGVLFKAFTNACQALELTNAEASHIIGVNPSTLSRNAANGFKPESKQGELQLQLVRLYRSLYALAGGQQDF
MRHWLNSPNHALGGIPRELVKSVVGLVSVNQYLDAMRGKV

Download         Length: 363 bp

>AT211868 NZ_CP106810:c2538-2353 [Neisseria gonorrhoeae]
ATGCAAACCACTATCCCCACCGGTTCAATCCGCACCTTTGGCGATTACGGCGTGATGTACATCGTCGGCACGCCTGCCGA
ACAGCTTCCGGACGGCGATTGGCTCGTAAATATTGAACTGCCGGAAAGCGGCGAACACACGCAATACAAACTGTCCCACA
TCGTTCAAGACCCAAAGGCTGCCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References