211865

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ygfYX/Cpta(toxin)
Location 2955464..2956133 Replicon chromosome
Accession NZ_CP080413
Organism Shewanella acanthi strain FJAT-51860

Toxin (Protein)


Gene name ygfX Uniprot ID -
Locus tag K0H61_RS12770 Protein ID WP_220049735.1
Coordinates 2955464..2955904 (-) Length 147 a.a.

Antitoxin (Protein)


Gene name ygfY Uniprot ID -
Locus tag K0H61_RS12775 Protein ID WP_220049736.1
Coordinates 2955885..2956133 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K0H61_RS12745 (K0H61_12745) 2951001..2951468 - 468 WP_220049730.1 SoxR reducing system RseC family protein -
K0H61_RS12750 (K0H61_12750) 2951476..2952408 - 933 WP_220049731.1 MucB/RseB C-terminal domain-containing protein -
K0H61_RS12755 (K0H61_12755) 2952421..2953029 - 609 WP_220049732.1 RseA family anti-sigma factor -
K0H61_RS12760 (K0H61_12760) 2953056..2953634 - 579 WP_220049733.1 RNA polymerase sigma factor RpoE -
K0H61_RS12765 (K0H61_12765) 2953824..2955437 + 1614 WP_220049734.1 L-aspartate oxidase -
K0H61_RS12770 (K0H61_12770) 2955464..2955904 - 441 WP_220049735.1 protein YgfX Toxin
K0H61_RS12775 (K0H61_12775) 2955885..2956133 - 249 WP_220049736.1 succinate dehydrogenase assembly factor 2 Antitoxin
K0H61_RS12780 (K0H61_12780) 2956217..2957125 - 909 WP_220049737.1 transcriptional activator NhaR -
K0H61_RS12785 (K0H61_12785) 2957218..2957604 - 387 WP_220049738.1 hypothetical protein -
K0H61_RS12790 (K0H61_12790) 2957601..2958776 - 1176 WP_220049739.1 Na+/H+ antiporter NhaA -
K0H61_RS12795 (K0H61_12795) 2958894..2959688 - 795 WP_220049740.1 thymidylate synthase -
K0H61_RS12800 (K0H61_12800) 2959688..2960494 - 807 WP_220049741.1 prolipoprotein diacylglyceryl transferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(5-135)

Antitoxin

Flavinator of succinate dehydrogenase

(7-77)


Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 17140.99 Da        Isoelectric Point: 8.6987

>T211865 WP_220049735.1 NZ_CP080413:c2955904-2955464 [Shewanella acanthi]
VEERRHSFSVSSSFDQRLSLVVFILVCSTSFLVWPSPDNLLLRLFKYVLIAVVFVFLIHSLWRLGDWQRRFSLNANGEGR
LEDGEVFYILKETRVTPFVCLIYYVANDKKQLLPIWADMLSDTDYRHLCRLLLQAKTKQAKSHLET

Download         Length: 441 bp

>T211865 NZ_CP106808:1597-1875 [Neisseria gonorrhoeae]
ATGTACGCGATTTCTTTTGATTTGGTGGTTGCCGATACCGCTCAAAACCATCCGAAAGGCATTTCCCAAGCCTACGCGGA
TATTGGATACACCCTGCGGAAATTCGGCTTTACCCGCATTCAGGGAAGTTTGTACACCTGCCAAAACGAAGATATGGCTA
ACCTGTTTTCAGCCATCAACGAGCTAAAAGCTCTGCCTTGGTTTCCGTCTTCTGTCCGCGATATTCGGGCGTTCCGCATT
GAGCAGTGGTCTGATTTCACAAGTCTTGTGAAGTCTTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9572.13 Da        Isoelectric Point: 4.4488

>AT211865 WP_220049736.1 NZ_CP080413:c2956133-2955885 [Shewanella acanthi]
MELMNIARVRWACRRGMLELDVLFQPFVENVYQQLSDEDKALFVRLLECEDPELFAWFMGHEACPDAELARMVVQVRGRA
AP

Download         Length: 249 bp

>AT211865 NZ_CP106808:1412-1597 [Neisseria gonorrhoeae]
ATGCAAACCACTATCCCCACCGGTTCAATCCGCACCTTTGGCGATTACGGCGTGATGTACATCGTCGGCACGCCTGCCGA
ACAGCTTCCGGACGGCGATTGGCTCGTAAATATTGAACTGCCGGAAAGCGGCGAACACACGCAATACAAACTGTCCCACA
TCGTTCAAGACCCAAAGGCTGCCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References