Detailed information of TA system TA211863

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ygfYX/Cpta(toxin)
• Location: 3466801..3467470
• Replicon: chromosome
• Accession: NZ_CP080412
• Organism: Shewanella mangrovisoli strain FJAT-51754

Toxin (Protein)

• Gene name: ygfX
• Uniprot ID: -
• Locus tag: K0H60_RS20615
• Protein ID: WP_258405750.1
• Coordinates: 3466801..3467241 (-)
• Length: 147 a.a.

Antitoxin (Protein)

• Gene name: ygfY
• Uniprot ID: -
• Locus tag: K0H60_RS15200
• Protein ID: WP_084294861.1
• Coordinates: 3467222..3467470 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K0H60_RS15175 (K0H60_15175)	3462249..3462722	-	474	WP_220056243.1	SoxR reducing system RseC family protein	-
K0H60_RS15180 (K0H60_15180)	3462734..3463666	-	933	WP_220053615.1	MucB/RseB C-terminal domain-containing protein	-
K0H60_RS15185 (K0H60_15185)	3463679..3464302	-	624	WP_220056244.1	RseA family anti-sigma factor	-
K0H60_RS15190 (K0H60_15190)	3464329..3464907	-	579	WP_011623604.1	RNA polymerase sigma factor RpoE	-
K0H60_RS15195 (K0H60_15195)	3465097..3466710	+	1614	WP_086903302.1	L-aspartate oxidase	-
K0H60_RS20615	3466801..3467241	-	441	WP_258405750.1	hypothetical protein	Toxin
K0H60_RS15200 (K0H60_15200)	3467222..3467470	-	249	WP_084294861.1	succinate dehydrogenase assembly factor 2	Antitoxin
K0H60_RS15205 (K0H60_15205)	3467553..3468461	-	909	WP_011717881.1	transcriptional activator NhaR	-
K0H60_RS15210 (K0H60_15210)	3468557..3468943	-	387	WP_220053620.1	hypothetical protein	-
K0H60_RS15215 (K0H60_15215)	3468946..3470115	-	1170	WP_088210495.1	Na+/H+ antiporter NhaA	-
K0H60_RS15220 (K0H60_15220)	3470233..3471027	-	795	WP_220056245.1	thymidylate synthase	-
K0H60_RS15225 (K0H60_15225)	3471027..3471833	-	807	WP_011717885.1	prolipoprotein diacylglyceryl transferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (5-134)

Antitoxin

• Flavinator of succinate dehydrogenase (7-77)

Sequences

Toxin

Protein

• Length: 147 a.a.
• Molecular weight: 17097.02 Da
• Isoelectric Point: 8.6460

>T211863 WP_258405750.1 NZ_CP080412:c3467241-3466801 [Shewanella mangrovisoli]
VAERRHSFSVKASRDQRLSLVVFVCVCSTSLLIWPETDVVFWRVLKLVFAVLILGFLGYQLWRLRTWQCRFELNGKGEGW
LSTEEAFHVLPRTWVTPFICLVYYQSADKLHLLPLWADMFSDTDYRHLCRLLLKVKTQATSQGESL

Nucleotide

• Length: 441 bp

>T211863 NZ_CP106807:661546-661965 [Neisseria gonorrhoeae]
ATGATTTTGCTGGACACGAATGTGATTTCCGAACCTTTGCGCCCACAACCCAATGAACGTGTGGTGGCATGGTTGGATAG
TTTGATATTGGAAGATGTGTATTTGTCTGCCATTACTGTTGCAGAATTGCGTTTGGGTGTGGCGTTGTTGCTCAATGGCA
AGAAAAAGAATGTGCTGCACGAACGTTTGGAACAATCCATTTTGCCTTTATTTGCGGGGCGGATTCTGCCTTTTGATGAA
CCGGTTGCCGCAATCTATGCGCAAATTCGTTCCTATGCCAAAACACATGGCAAAGAGATTGCTGCCGCAGACGGCTATAT
TGCCGCCACTGCAAAACAGCACAGTTTGACAGTTGCTACGCGTGATACCGGCTCATTTTTTGCGGCCGATGTCGCGGTGT
TCAATCCGTGGCACGATTAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9559.09 Da
• Isoelectric Point: 4.3313

>AT211863 WP_084294861.1 NZ_CP080412:c3467470-3467222 [Shewanella mangrovisoli]
MELMNIARVRWACRRGMLELDVLFQPFVENVYQDLSDDDKALFIRLLECEDPELFAWFMGHEACPDAELARMVVQVRGRA
AP

Nucleotide

• Length: 249 bp

>AT211863 NZ_CP106807:661310-661546 [Neisseria gonorrhoeae]
ATGGCTTCTGTTGTGATTAGAAATTTATCCGAGGCCACGCACAACGCAATCAAATTCCGTGCGCGAGCCGCAGGGCGCAG
TACCGAAGCAGAAATCCGCTTAATTTTGGATAACATCGCCAAAGCACAACAAACTGTACGTTTGGGGTCAATGTTGGCAT
CAATAGGGCAGGAAATCGGAGGTGTTGAGCTGGAAGACGTACGCGGTCGTAATACTGATAACGAGGTTTCTTTGTGA