211862

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ygfYX/Cpta(toxin)
Location 3480380..3481049 Replicon chromosome
Accession NZ_CP080411
Organism Shewanella sp. FJAT-51649

Toxin (Protein)


Gene name ygfX Uniprot ID -
Locus tag K0H59_RS15325 Protein ID WP_220053618.1
Coordinates 3480380..3480820 (-) Length 147 a.a.

Antitoxin (Protein)


Gene name ygfY Uniprot ID -
Locus tag K0H59_RS15330 Protein ID WP_084294861.1
Coordinates 3480801..3481049 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K0H59_RS15300 (K0H59_15300) 3475828..3476301 - 474 WP_220053614.1 SoxR reducing system RseC family protein -
K0H59_RS15305 (K0H59_15305) 3476313..3477245 - 933 WP_220053615.1 MucB/RseB C-terminal domain-containing protein -
K0H59_RS15310 (K0H59_15310) 3477258..3477881 - 624 WP_220053616.1 RseA family anti-sigma factor -
K0H59_RS15315 (K0H59_15315) 3477908..3478486 - 579 WP_011623604.1 RNA polymerase sigma factor RpoE -
K0H59_RS15320 (K0H59_15320) 3478676..3480289 + 1614 WP_220053617.1 L-aspartate oxidase -
K0H59_RS15325 (K0H59_15325) 3480380..3480820 - 441 WP_220053618.1 hypothetical protein Toxin
K0H59_RS15330 (K0H59_15330) 3480801..3481049 - 249 WP_084294861.1 succinate dehydrogenase assembly factor 2 Antitoxin
K0H59_RS15335 (K0H59_15335) 3481132..3482040 - 909 WP_220053619.1 transcriptional activator NhaR -
K0H59_RS15340 (K0H59_15340) 3482136..3482522 - 387 WP_220053620.1 hypothetical protein -
K0H59_RS15345 (K0H59_15345) 3482525..3483694 - 1170 WP_088210495.1 Na+/H+ antiporter NhaA -
K0H59_RS15350 (K0H59_15350) 3483812..3484606 - 795 WP_086903299.1 thymidylate synthase -
K0H59_RS15355 (K0H59_15355) 3484606..3485412 - 807 WP_011717885.1 prolipoprotein diacylglyceryl transferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(5-134)

Antitoxin

Flavinator of succinate dehydrogenase

(7-77)


Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 17006.93 Da        Isoelectric Point: 8.6480

>T211862 WP_220053618.1 NZ_CP080411:c3480820-3480380 [Shewanella sp. FJAT-51649]
VAERRHSFSIKASSDQRLSLVVFVCVCSTSLLIWPETDVVFWLVLKLVFAVLILGFLGYQLWRLRSWHCRFELNGKGEGW
LSTGEAFHVLPRTWVTPFVCLVYYQSADKLHLLPLWADMFSDTDYRHLCRLLLKVKTQATSQRESL

Download         Length: 441 bp

>T211862 NZ_CP106806:c1114-836 [Neisseria gonorrhoeae]
ATGTACGCGATTTCTTTTGATTTGGTGGTTGCCGATACCGCTCAAAACCATCCGAAAGGCATTTCCCAAGCCTACGCGGA
TATTGGATACACCCTGCGGAAATTCGGCTTTACCCGCATTCAGGGAAGTTTGTACACCTGCCAAAACGAAGATATGGCTA
ACCTGTTTTCAGCCATCAACGAGCTAAAAGCTCTGCCTTGGTTTCCGTCTTCTGTCCGCGATATTCGGGCGTTCCGCATT
GAGCAGTGGTCTGATTTCACAAGTCTTGTGAAGTCTTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9559.09 Da        Isoelectric Point: 4.3313

>AT211862 WP_084294861.1 NZ_CP080411:c3481049-3480801 [Shewanella sp. FJAT-51649]
MELMNIARVRWACRRGMLELDVLFQPFVENVYQDLSDDDKALFIRLLECEDPELFAWFMGHEACPDAELARMVVQVRGRA
AP

Download         Length: 249 bp

>AT211862 NZ_CP106806:c1299-1114 [Neisseria gonorrhoeae]
ATGCAAACCACTATCCCCACCGGTTCAATCCGCACCTTTGGCGATTACGGCGTGATGTACATCGTCGGCACGCCTGCCGA
ACAGCTTCCGGACGGCGATTGGCTCGTAAATATTGAACTGCCGGAAAGCGGCGAACACACGCAATACAAACTGTCCCACA
TCGTTCAAGACCCAAAGGCTGCCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References