Detailed information of TA system TA211855

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 3422775..3423409
• Replicon: chromosome
• Accession: NZ_CP080400
• Organism: Dickeya fangzhongdai strain Onc5

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: K0H75_RS14790
• Protein ID: WP_038919729.1
• Coordinates: 3423005..3423409 (+)
• Length: 135 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: K0H75_RS14785
• Protein ID: WP_038919728.1
• Coordinates: 3422775..3423005 (+)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K0H75_RS14775 (K0H75_14755)	3419718..3420826	+	1109	Protein_2898	IS3 family transposase	-
K0H75_RS14780 (K0H75_14760)	3421020..3422441	-	1422	WP_231348807.1	DUF2235 domain-containing protein	-
K0H75_RS14785 (K0H75_14765)	3422775..3423005	+	231	WP_038919728.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
K0H75_RS14790 (K0H75_14770)	3423005..3423409	+	405	WP_038919729.1	tRNA(fMet)-specific endonuclease VapC	Toxin
K0H75_RS14795 (K0H75_14775)	3423686..3426931	-	3246	WP_038919730.1	type I Zorya anti-phage system protein ZorD	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3420473..3433323	12850
	-	flank	IS/Tn	-	-	3419718..3419984	266

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (4-124)

Antitoxin

• SpoVT-AbrB domain (7-54)

Sequences

Toxin

Protein

• Length: 135 a.a.
• Molecular weight: 15085.32 Da
• Isoelectric Point: 7.9926

>T211855 WP_038919729.1 NZ_CP080400:3423005-3423409 [Dickeya fangzhongdai]
MLKYLLDTNICIYTIKNKPQEVRDAFYRYYGQFAISAITLMELIYGAEKSVNPEKNLAVIEGFSARLEVQTYGFDAAVHT
GQIRAELARQGTPIGPYDAMLAGHARSAGLILVTNNVREFERVPGLRVENWVSR

Nucleotide

• Length: 405 bp

>T211855 NZ_CP106801:c1644595-1644413 [Neisseria gonorrhoeae]
TTGAATAGCCTAGACGTTATTGCCCTACTCAAACAAGACGGTTGGTATAAAGTTGCACAATCCGGGAGCCATTCGCAATA
TAAGCACCCAACAAAAAAAGGCCGTGTAACCGTGCCGCACCCGAAAAAAGACTTGCCGACAGGTACTGTAAAAAATATCT
ATAAGCAAGCCGGTTTGAAGTAA

Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 8708.78 Da
• Isoelectric Point: 4.3193

>AT211855 WP_038919728.1 NZ_CP080400:3422775-3423005 [Dickeya fangzhongdai]
MEKTTVFKSNRSQAVRLPKAVALPDDVKQVDIVAIGRTRIITPAGESWDSWFEEEGVTPDFMITREQPDDQIREDF

Nucleotide

• Length: 231 bp

>AT211855 NZ_CP106801:c1644311-1643910 [Neisseria gonorrhoeae]
ATGTTTATCCCTGCCGCCCTGCACAAAGACGAACATTCGGCATATGGCGTAACCATCCCCGACCTTCCCGGCTGTTTCTC
TTGCGGCGACACCGTTGAAGAAGCCGTCGCCAACGCCCGTTCTGCCGCCTATATGCATATTGACGGTATGATTGAGGACG
GAGGGTTCAAAAACCTTGCCGTAAGCAGCATTGCCGATTTGAGCCAAGAACCTGATTATCATGGGGCAACATGGGTAATG
ATTGAAATCGACCCTGCAAAAATCAGTCGGCAGCAAATCCGATTCAACGTCAGCTGGCCGCAATACCTTCTTGATAGAGT
GGATGAATATACATCCGCAAATCATGAAACCCGTAGCGGTTTTTTAGCCAAAGCCGCCCTGCTCACCATGAATCAGGCAT
AG