211840

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 425318..426354 Replicon chromosome
Accession NZ_CP080400
Organism Dickeya fangzhongdai strain Onc5

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag K0H75_RS01945 Protein ID WP_038917617.1
Coordinates 425779..426354 (+) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag K0H75_RS01940 Protein ID WP_038917616.1
Coordinates 425318..425779 (+) Length 154 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K0H75_RS01920 (K0H75_01920) 420488..421411 + 924 WP_038917612.1 type I-E CRISPR-associated endonuclease Cas1e -
K0H75_RS01925 (K0H75_01925) 421408..421701 + 294 WP_038917614.1 type I-E CRISPR-associated endoribonuclease Cas2e -
K0H75_RS01930 (K0H75_01930) 423094..424770 - 1677 WP_038917615.1 methyl-accepting chemotaxis protein -
K0H75_RS01935 424942..425052 - 111 Protein_372 hypothetical protein -
K0H75_RS01940 (K0H75_01935) 425318..425779 + 462 WP_038917616.1 helix-turn-helix domain-containing protein Antitoxin
K0H75_RS01945 (K0H75_01940) 425779..426354 + 576 WP_038917617.1 PIN domain-containing protein Toxin
K0H75_RS01950 (K0H75_01945) 426578..427030 + 453 WP_038917619.1 YhbP family protein -
K0H75_RS01955 (K0H75_01950) 427142..427606 - 465 WP_038917620.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
K0H75_RS01960 (K0H75_01955) 427705..429843 - 2139 WP_038917621.1 anaerobic ribonucleoside-triphosphate reductase -
K0H75_RS01965 (K0H75_01960) 430223..431131 + 909 WP_038917622.1 homocysteine S-methyltransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-115)

Antitoxin

SinI-like, DNA-binding domain

(84-131)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21629.93 Da        Isoelectric Point: 4.8531

>T211840 WP_038917617.1 NZ_CP080400:425779-426354 [Dickeya fangzhongdai]
MTHTPYPVVLDACVIYPSLLRDLLIHLGLTGLYQPKWTAIIEDEWQRNLLLNRPDLTPEQISRTRELMNQAIPDAMITGF
EALIPGITLPDPDDQHVVAAAIRSNAEIIVTFNLKDFPHPEIDNFGIEALHPDDFITDLLDLNQALVLSAVSRQRHSMRK
PPKSVDEYLDALLRQSLPQTVKELSKFHALI

Download         Length: 576 bp

>T211840 NZ_CP106786:c3941300-3940983 [Klebsiella pneumoniae]
ATGTTCAGATTGGTTGTGCATGTGGACGTTAAAAAGGAATTGCAGGCGCTTCCGTCCATTGTCCAGGCGAAGATGATCCG
GCAATTAGACAAGTTACGCCAAAATCCCACCGCGCTGAGAGAACCTGACAGTAAACCGCTGGGGCAGGGGCTATTTGAAA
TTCGTGCGTTAGGTTCGGTACAGGGGCGAGGGATCTACGTTTTTCAGCAAGGCAAGACGCTCTTTCTGCTACGGGTTTTT
GTCAAGAAAACGCAAAAAACCCCGTCATCGGAAATTCGCCTGGCGCTGAAGCGATTAGAGGAGATGCGCAATGAGTAA

Antitoxin


Download         Length: 154 a.a.        Molecular weight: 16913.27 Da        Isoelectric Point: 6.2221

>AT211840 WP_038917616.1 NZ_CP080400:425318-425779 [Dickeya fangzhongdai]
MTNSILDSLSLPAPGEIEAAVRGQRELAAYLSTKMETQKISIQDADNNTRQVELPTSALTLLMSILGELAVGNAVQVVPV
HAELTTQEAANILNVSRPHMVKLLEDGKLPFHKTGRHRRVLFADLMDYKHQRDNESSRAMQALADHSQELGLY

Download         Length: 462 bp

>AT211840 NZ_CP106786:c3940990-3940703 [Klebsiella pneumoniae]
ATGAGTAAAAAGATCATTGACTGGGATACGTTAAAAACAGAACTGCTTGGCCAGCCTGAGGTTCAGGCTGCATTCGATGC
GCAAGAACGTCAACAGCGATTACGTACTATGCTGGCGCAATGGCGCGAGCAGGCGGGGCTAACCCGAGCCCAGGTGGCGC
AGAGGATGGGGGTGAGTGCGCCGACGGTCTCCAGAATGGAAGCCAATATCACCCGCGCCAGTCTGGATACCTTAACGCGA
TACGCGTTAGCCTGCGGTATAAAGCACCCGCAAGTTTTACTTTACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References