Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2017531..2017802 Replicon chromosome
Accession NZ_CP080370
Organism Escherichia coli strain PK5086

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2017661..2017764 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2017531..2017802 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K0H55_RS09680 2014086..2014748 - 663 WP_000944256.1 exodeoxyribonuclease X -
K0H55_RS09685 2014772..2015428 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
K0H55_RS09690 2015530..2015760 - 231 WP_000916763.1 DNA polymerase III subunit theta -
K0H55_RS09695 2015899..2016273 + 375 WP_000204699.1 CopC domain-containing protein YobA -
K0H55_RS09700 2016277..2017149 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
K0H55_RS09705 2017162..2017503 + 342 WP_000976492.1 YebY family protein -
- 2017531..2017802 - 272 - - Antitoxin
- 2017661..2017764 + 104 - - Toxin
K0H55_RS09710 2017899..2018555 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
K0H55_RS09715 2018556..2018747 - 192 WP_001296140.1 YebW family protein -
K0H55_RS09720 2018852..2019088 - 237 WP_001295499.1 YebV family protein -
K0H55_RS09725 2019206..2020645 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T211805 NZ_CP080370:2017661-2017764 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT211805 NZ_CP080370:c2017802-2017531 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References