Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1879982..1880127 Replicon chromosome
Accession NZ_CP080362
Organism Klebsiella pneumoniae strain K191773

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1880018..1880120 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1879982..1880127 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K0P53_RS09275 1875112..1877172 + 2061 WP_004151449.1 oligopeptidase B -
K0P53_RS09280 1877176..1877835 - 660 WP_002911407.1 exodeoxyribonuclease X -
K0P53_RS09285 1877914..1878144 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K0P53_RS09290 1878257..1878631 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K0P53_RS09295 1878635..1879504 + 870 WP_009307538.1 copper homeostasis membrane protein CopD -
K0P53_RS09300 1879521..1879859 + 339 WP_009307539.1 YebY family protein -
- 1879982..1880127 - 146 - - Antitoxin
- 1880018..1880120 + 103 - - Toxin
K0P53_RS09305 1880496..1880639 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K0P53_RS09310 1880744..1881712 - 969 WP_004151446.1 VirK/YbjX family protein -
K0P53_RS09315 1881869..1882522 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
K0P53_RS09320 1882519..1882710 - 192 WP_002911395.1 YebW family protein -
K0P53_RS09325 1882808..1883047 - 240 WP_002911393.1 YebV family protein -
K0P53_RS09330 1883163..1884596 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T211766 NZ_CP080362:1880018-1880120 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT211766 NZ_CP080362:c1880127-1879982 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References